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Titolo:
Effect of oral midazolam premedication on the awakening concentration of sevoflurane, recovery times and bispectral index in children
Autore:
Brosius, KK; Bannister, CF;
Indirizzi:
Emory Univ, Sch Med, Childrens Healthcare Atlanta, Dept Anesthesiol, Atlanta, GA 30322 USA Emory Univ Atlanta GA USA 30322 , Dept Anesthesiol, Atlanta, GA 30322 USA
Titolo Testata:
PAEDIATRIC ANAESTHESIA
fascicolo: 5, volume: 11, anno: 2001,
pagine: 585 - 590
SICI:
1155-5645(200109)11:5<585:EOOMPO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
PREANESTHETIC MEDICATION; ANESTHESIA; SEDATION; ALFENTANIL; PROPOFOL; ISOFLURANE; DEPTH; BIS;
Keywords:
bispectral index (BIS); premedication; midazolam; anaesthesia, general;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Brosius, KK Emory Univ, Sch Med, Childrens Healthcare Atlanta, Dept Anesthesiol, 1405 Clifton Rd NE, Atlanta, GA 30322 USA Emory Univ 1405 Clifton RdNE Atlanta GA USA 30322 A 30322 USA
Citazione:
K.K. Brosius e C.F. Bannister, "Effect of oral midazolam premedication on the awakening concentration of sevoflurane, recovery times and bispectral index in children", PAEDIATR AN, 11(5), 2001, pp. 585-590

Abstract

Background: We sought to determine the influence of preoperative oral midazolam on: (i) measures of anaesthetic emergence; (ii) recovery times and (iii) intraoperative bispectral index (BIS) measurements during sevoflurane/N2O anaesthesia in paediatric patients. Methods: Fifty-two patients, aged 1-10 years, ASA I-II, were enrolled in aprospective double-blinded study. Patients were randomized to receive either midazolam 0.5 mg.kg(-1) (M) or midazolam vehicle (P) as premedication. After inhalation induction and intubation, expired sevoflurane was stabilized at 3% in 60% N2O and the corresponding BIS (BIS I) recorded. At the completion of surgery, sevoflurane was stabilized at 0.5% and the BIS (BIS E) again recorded. Awakening time, expired sevoflurane/N2O awakening concentrations and recovery times were recorded. Results: There were no significant differences between groups in awakeningtime, sevoflurane or N2O awakening concentrations, time to PACU discharge,time to hospital discharge or in BIS I and BIS E measurements.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:09:24