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Titolo:
GM-CSF antagonists
Autore:
Williams, WV;
Indirizzi:
SmithKline Beecham, Clin Pharmacol, Philadelphia, PA 19104 USA SmithKline Beecham Philadelphia PA USA 19104 , Philadelphia, PA 19104 USA
Titolo Testata:
NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
, volume: 31, anno: 2001,
pagine: 251 - 255
SICI:
1422-2140(2001)31:<251:GA>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLONY-STIMULATING FACTOR; PULMONARY ALVEOLAR PROTEINOSIS; FACTOR-DEFICIENT MICE; RECEPTOR ALPHA-CHAIN; COMMON BETA-SUBUNIT; TYROSINE PHOSPHORYLATION; SIGNAL-TRANSDUCTION; MOLECULAR-CLONING; IMMUNE-RESPONSE; IL-5 RECEPTORS;
Tipo documento:
Article
Natura:
Collana
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Williams, WV SmithKline Beecham, Clin Pharmacol, 51 N 39th St, Philadelphia, PA 19104 USA SmithKline Beecham 51 N 39th St Philadelphia PA USA 19104 USA
Citazione:
W.V. Williams, "GM-CSF antagonists", PROG R RES, 31, 2001, pp. 251-255

Abstract

GM-CSF is an important growth factor which shares many of the properties of cytokines and chemokines. GM-CSF is currently used therapeutically as a recombinant protein given parenterally to enhance the function and maturation of myeloid cells. GM-CSF has also been linked to a number of disease states characterized by hyperactivity of myeloid cells. In this review, the receptor interactions of GM-CSF will be described as well as the bioactivity of GM-CSF and its role in disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 14:41:38