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Titolo:
Cytokines: An overview
Autore:
Chung, KF;
Indirizzi:
Univ London Imperial Coll Sci Technol & Med, Sch Med, Natl Heart & Lung Inst, London SW3 6LY, England Univ London Imperial Coll Sci Technol & Med London England SW3 6LY gland
Titolo Testata:
NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
, volume: 31, anno: 2001,
pagine: 242 - 246
SICI:
1422-2140(2001)31:<242:CAO>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLONY-STIMULATING FACTOR; CHRONIC-BRONCHITIS; HUMAN EOSINOPHILS; FUNCTIONAL-PROPERTIES; ASTHMA; MACROPHAGE; INTERLEUKIN-5; EXPRESSION; CELL; COPD;
Tipo documento:
Article
Natura:
Collana
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Chung, KF Univ London Imperial Coll Sci Technol & Med, Sch Med, Natl Heart& Lung Inst, Dovehouse St, London SW3 6LY, England Univ London Imperial Coll Sci Technol & Med Dovehouse St London England SW3 6LY
Citazione:
K.F. Chung, "Cytokines: An overview", PROG R RES, 31, 2001, pp. 242-246

Abstract

Cytokines are likely to play important roles in the chronic inflammatory processes and airway wall remodelling of asthma and COPD. They have a wide variety of effects, including cell activation and proliferation, maturation of haematopoietic cells, chemoattraction and migration, adhesion, immune regulation and cell survival or apoptosis. In relation to asthma and COPD, cytokines may induce eosinophilic or neutrophilic airway inflammation, subepithelial fibrosis, goblet cell hyperplasia and increases in mucin expression, matrix metalloproteinases and bronchial hyperresponsiveness. Targetting specific cytokines may lead to much-needed novel therapies for asthma and COPD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:23:36