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Titolo:
Anti-IgE antibody
Autore:
Boushey, HA; Fick, R; Fahy, JV;
Indirizzi:
Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA Univ CalifSan Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA
Titolo Testata:
NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
, volume: 31, anno: 2001,
pagine: 201 - 205
SICI:
1422-2140(2001)31:<201:AA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL-DEFICIENT MICE; MURINE MODEL; SERUM IGE; AIRWAY HYPERRESPONSIVENESS; MONOCLONAL-ANTIBODY; ALLERGIC RHINITIS; AFFINITY RECEPTOR; HUMAN BASOPHILS; ASTHMA; INFLAMMATION;
Tipo documento:
Article
Natura:
Collana
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Boushey, HA Univ Calif San Francisco, Dept Med, Box 0130,1292-M,505 Parnassus Ave, SanFrancisco, CA 94143 USA Univ Calif San Francisco Box 0130,1292-M,505 Parnassus Ave San Francisco CA USA 94143
Citazione:
H.A. Boushey et al., "Anti-IgE antibody", PROG R RES, 31, 2001, pp. 201-205

Abstract

This brief review summarizes the rationale for selecting IgE as a target appropriate for specific therapy, the development and preclinical testing ofa selective monoclonal anti-IgE antibody, the demonstration of its safety and efficacy in a clinical model, and, finally, the demonstration of the antibody's safety and efficacy in a large clinical trial.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:19:26