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Titolo:
Dissociated steroids
Autore:
Brown, TJ; Belvisi, MG; Foster, ML;
Indirizzi:
Aventis Pharmaceut, Dagenham, England Aventis Pharmaceut Dagenham England entis Pharmaceut, Dagenham, England
Titolo Testata:
NEW DRUGS FOR ASTHMA, ALLERGY AND COPD
, volume: 31, anno: 2001,
pagine: 98 - 101
SICI:
1422-2140(2001)31:<98:DS>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLUCOCORTICOID RECEPTOR; DNA-BINDING; IN-VIVO; MECHANISMS; REPRESSION; ASTHMA; AP-1;
Tipo documento:
Article
Natura:
Collana
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Belvisi, MG Natl Heart & Lung Inst, Sch Med, Imperial Coll, Resp PharmacolGrp, Dovehouse St, London SW3 6LY, England Natl Heart & Lung Inst Dovehouse St London England SW3 6LY nd
Citazione:
T.J. Brown et al., "Dissociated steroids", PROG R RES, 31, 2001, pp. 98-101

Abstract

Inhaled glucocorticoids are the mainstay of asthma therapy, but their use is often limited by the associated systemic side effects. Dissociated steroids have been developed which differentiate between the two main actions ofsteroids (i.e. transactivation and transrepression). These compounds claimto offer the potential for a more selective anti-inflammatory profile without possessing adverse effects. The profile of one such compound is discussed below.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:39:20