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Titolo:
Transient expression of phospholipase D1 in developing rat hippocampus
Autore:
Min, DS; Choi, JS; Chun, MH; Chung, JW; Lee, MY;
Indirizzi:
Catholic Univ Korea, Coll Med, Dept Anat, Socho Gu, Seoul 137701, South Korea Catholic Univ Korea Seoul South Korea 137701 , Seoul 137701, South Korea Catholic Univ Korea, Coll Med, Dept Physiol, Seoul 137701, South Korea Catholic Univ Korea Seoul South Korea 137701 , Seoul 137701, South Korea
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 2-3, volume: 310, anno: 2001,
pagine: 125 - 128
SICI:
0304-3940(20010914)310:2-3<125:TEOPDI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER-RNA LEVELS; INDUCED APOPTOSIS; CELLS; DIFFERENTIATION; LOCALIZATION; BRAIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Lee, MY Catholic Univ Korea, Coll Med, Dept Anat, Socho Gu, 505 Banpo Dong, Seoul 137701, South Korea Catholic Univ Korea 505 Banpo Dong Seoul SouthKorea 137701 Korea
Citazione:
D.S. Min et al., "Transient expression of phospholipase D1 in developing rat hippocampus", NEUROSCI L, 310(2-3), 2001, pp. 125-128

Abstract

We investigated the distribution of phospholipase Di (PLD1) protein in thedeveloping rat hippocampus using an affinity-purified peptide antibody against PLD1. Immunoreactivity for PLD1 was first seen in some scattered cellsin the hippocampus at embryonic day 18. At postnatal day 1 (P1), many PLD1immunoreactive cells were observed in the CA1 and CA3 sectors, subiculum and the hilus of the dentate gyrus. During the first postnatal week, there was an abrupt increase of immunoreactive neurons in the hippocampus, and their number and intensity peaked at P7. During the second postnatal week, there was an abrupt decrease in the number of immunoreactive hippocampal neurons. By P14, no significant labeling was found in the hippocampus. These results corresponded well with those from Western blot analysis, suggesting that PLD1 may regulate the developmental processes of hippocampal neurons. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 09:04:47