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Titolo:
Re-evaluating centrosome function
Autore:
Doxsey, S;
Indirizzi:
Univ Massachusetts, Sch Med, Program Mol Med, Worcester, MA 01605 USA UnivMassachusetts Worcester MA USA 01605 ol Med, Worcester, MA 01605 USA
Titolo Testata:
NATURE REVIEWS MOLECULAR CELL BIOLOGY
fascicolo: 9, volume: 2, anno: 2001,
pagine: 688 - 698
SICI:
1471-0072(200109)2:9<688:RCF>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
GAMMA-TUBULIN COMPLEXES; SPINDLE POLE BODY; SPISULA-SOLIDISSIMA OOCYTES; XENOPUS EGG EXTRACTS; MICROTUBULE NUCLEATION; MITOTIC SPINDLE; CYTOPLASMIC DYNEIN; RING COMPLEX; CELL-CYCLE; SACCHAROMYCES-CEREVISIAE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
128
Recensione:
Indirizzi per estratti:
Indirizzo: Doxsey, S Univ Massachusetts, Sch Med, Program Mol Med, 373 Plantat St, Worcester, MA 01605 USA Univ Massachusetts 373 Plantat St Worcester MA USA 01605 605 USA
Citazione:
S. Doxsey, "Re-evaluating centrosome function", NAT REV MOL, 2(9), 2001, pp. 688-698

Abstract

Over the past 100 years, the centrosome has risen in status from an enigmatic organelle, located at the focus of microtubules, to a key player in cell-cycle progression and cellular control. A growing body of evidence indicates that centrosomes might not be essential for spindle assembly, whereas recent data indicate that they might be important for initiating S phase andcompleting cytokinesis. Molecules that regulate centrosome duplication have beer identified, and the expanding list of intriguing centrosome-anchoredactivities, the functions of which have yet to be determined, promises continued discovery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 15:25:23