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Titolo:
Cocirculation of avian H9N2 and contemporary "human" H3N2 influenza A viruses in pigs in southeastern China: Potential for genetic reassortment?
Autore:
Peiris, JSM; Guan, Y; Markwell, D; Ghose, P; Webster, RG; Shortridge, KF;
Indirizzi:
Univ Hong Kong, Dept Microbiol, Pokfulam, Hong Kong Speci, Peoples R ChinaUniv Hong Kong Pokfulam Hong Kong Speci Peoples R China Peoples R China St Jude Childrens Hosp, Dept Virol & Mol Biol, Memphis, TN 38105 USA St Jude Childrens Hosp Memphis TN USA 38105 l Biol, Memphis, TN 38105 USA
Titolo Testata:
JOURNAL OF VIROLOGY
fascicolo: 20, volume: 75, anno: 2001,
pagine: 9679 - 9686
SICI:
0022-538X(200110)75:20<9679:COAHAC>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
TO-HUMAN TRANSMISSION; A H5N1 VIRUS; SOUTHERN CHINA; HONG-KONG; SWINE; HEMAGGLUTININ; NUCLEOPROTEIN; SPECIFICITY; EMERGENCE; INFECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Peiris, JSM Univ Hong Kong, Queen Mary Hosp, Dept Microbiol, Pokfulam, Hong Kong Speci, Peoples R China Univ Hong Kong Pokfulam Hong Kong Speci Peoples R China hina
Citazione:
J.S.M. Peiris et al., "Cocirculation of avian H9N2 and contemporary "human" H3N2 influenza A viruses in pigs in southeastern China: Potential for genetic reassortment?", J VIROLOGY, 75(20), 2001, pp. 9679-9686

Abstract

Pigs are permissive to both human and avian influenza viruses and have been proposed to be an intermediate host for the genesis of pandemic influenzaviruses through reassortment or adaptation of avian viruses. Prospective virological surveillance carried out between March 1998 and June 2000 in Hong Kong, Special Administrative Region, People's Republic of China, on pigs imported from southeastern China, provides the first evidence of interspecies transmission of avian H9N2 viruses to pigs and documents their cocirculation with contemporary human H3N2 (A/Sydney/5/97-like, Sydney97-like) viruses. All gene segments of the porcine H9N2 viruses were closely related to viruses similar to chicken/Beijing/1/94 (H9N2), duck/Hong KongIY280/97 (H9N2), and the descendants of the latter virus lineage. Phylogenetic analysis suggested that repeated interspecies transmission events bad occurred from the avian host to pigs. The Sydney97-like (H3N2) viruses isolated from pigs were related closely to contemporary human H3N2 viruses in all gene segments and had not undergone genetic reassortment. Cocirculation of avian H9N2 and human H3N2 viruses in pigs provides an opportunity for genetic reassortment leading to the emergence of viruses with pandemic potential.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 18:58:05