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Titolo:
QUANTITATIVE STUDIES OF MAGNETIZATION-TRANSFER BY SELECTIVE EXCITATION AND T-1 RECOVERY
Autore:
GOCHBERG DF; KENNAN RP; GORE JC;
Indirizzi:
YALE UNIV,SCH MED,DEPT DIAGNOST RADIOL,POB 208042 NEW HAVEN CT 06520
Titolo Testata:
Magnetic resonance in medicine
fascicolo: 2, volume: 38, anno: 1997,
pagine: 224 - 231
SICI:
0740-3194(1997)38:2<224:QSOMBS>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
HETEROGENEOUS SPIN SYSTEMS; TRANSFER CONTRAST; CROSS-RELAXATION; LONGITUDINAL MAGNETIZATION; TRANSIENT DECAY; PROTON NMR; MODEL; SATURATION; TISSUE; SUPPRESSION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
D.F. Gochberg et al., "QUANTITATIVE STUDIES OF MAGNETIZATION-TRANSFER BY SELECTIVE EXCITATION AND T-1 RECOVERY", Magnetic resonance in medicine, 38(2), 1997, pp. 224-231

Abstract

Water proton longitudinal relaxation has been measured in agar and cross-linked bovine serum albumin (BSA) using modified selective excitation (Goldman-Shen and Edzes-Samulski) pulse sequences. The resulting recovery curves are fit to biexponentials, The fast recovery rate givesmagnetization transfer (MT) information, which is complementary to that given by steady-state saturation methods, TL ris rate provides an estimate of the strength of the coupling of the immobile proton pool tothe mobile proton pool. Near their optimal pulse power values, the Goldman-Shen and Edzes-Samulski sequences give fast recovery rates that agree with each other, However, these measured fast recovery rates aredependent on the pulse power, an effect not predicted by the coupled two-pool model. For 8% agar and 17% BSA, both methods (at optimal pulse powers) give rates in the neighborhoods of 210 and 64 Hz, respectively, The Goldman-Shen and Edzes-Samulski pulse sequences have several advantages over those techniques based on steady state saturation: no long saturating pulses, shorter measurement time, and reduced necessityfor making lineshape or fitting technique assumptions. The principle disadvantages are smaller effects on the NMR signal, less complete characterization of the MT system, and, in the case of the Goldman-Shen sequence, greater pulse power.

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Documento generato il 06/07/20 alle ore 07:50:43