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Titolo:
Deep Brain Stimulation (DBS) attentional effects parallel those of l-dopa treatment
Autore:
Brusa, L; Pierantozzi, M; Peppe, A; Altibrandi, MG; Giacomini, P; Mazzone, P; Stanzione, P;
Indirizzi:
IRCCS, Fondaz S Lucia, I-00179 Rome, Italy IRCCS Rome Italy I-00179IRCCS, Fondaz S Lucia, I-00179 Rome, Italy Univ Roma Tor Vergata, Neurol Clin, Rome, Italy Univ Roma Tor Vergata Rome Italy Tor Vergata, Neurol Clin, Rome, Italy Osped CTO, Div Neurochirurg, Rome, Italy Osped CTO Rome ItalyOsped CTO, Div Neurochirurg, Rome, Italy Univ Roma La Sapienza, Ist Clin Malattie Nervose & Mentali, I-00185 Rome, Italy Univ Roma La Sapienza Rome Italy I-00185 & Mentali, I-00185 Rome, Italy
Titolo Testata:
JOURNAL OF NEURAL TRANSMISSION
fascicolo: 8-9, volume: 108, anno: 2001,
pagine: 1021 - 1027
SICI:
0300-9564(2001)108:8-9<1021:DBS(AE>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADVANCED PARKINSONS-DISEASE; SUBTHALAMIC NUCLEUS; POSTEROVENTRAL PALLIDOTOMY; PALLIDAL STIMULATION; FOLLOW-UP; MOTOR; PERFORMANCE; LEVODOPA;
Keywords:
DBS; l-dopa; attentional capacity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Stanzione, P IRCCS, Fondaz S Lucia, Via Ardeatina 306, I-00179 Rome, ItalyIRCCS Via Ardeatina 306 Rome Italy I-00179 00179 Rome, Italy
Citazione:
L. Brusa et al., "Deep Brain Stimulation (DBS) attentional effects parallel those of l-dopa treatment", J NEURAL TR, 108(8-9), 2001, pp. 1021-1027

Abstract

Aim of our study was to investigate the different effects on attentional capacity of deep brain stimulation DBS (STN or GPi) and of 1-dopa in PD patients. Patients were evaluated on-DBS/off-1-dopa, on-1-dopa/off-DBS, on-1-dopa/on-DBS and off-1-dopa/off-DBS. Our results indicate that DBS effects on attentional functions parallel those of 1-dopa. A site independent (both STN and GPi) worsening of verbal fluency was observed, possibly connected to the stimulus effect on the cortico-subcortical-cortical loop.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 07:40:18