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Titolo:
Brain metastases of malignant melanoma showing unbalanced whole arm chromosomal translocations der (8;14) (q10; q10) and der (11;15) (q10; q10) in a Japanese patient
Autore:
Takahashi, T; Kazama, Y; Shimizu, H; Yoshimoto, M; Tsujisaki, M; Imai, K;
Indirizzi:
Tenshi Hosp, Dept Internal Med 2, Higashi Ku, Sapporo, Hokkaido 0650012, Japan Tenshi Hosp Sapporo Hokkaido Japan 0650012 pporo, Hokkaido 0650012, Japan
Titolo Testata:
INTERNAL MEDICINE
fascicolo: 9, volume: 40, anno: 2001,
pagine: 956 - 963
SICI:
0918-2918(200109)40:9<956:BMOMMS>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
SWALLOW SYNCOPE; THROMBOSIS;
Keywords:
CT; chromosome analysis; lack of HLA-DR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Takahashi, T Tenshi Hosp, Dept Internal Med 2, Higashi Ku, Kita 12,Higashi3,31, Sapporo, Hokkaido 0650012, Japan Tenshi Hosp Kita 12,Higashi 3,31 Sapporo Hokkaido Japan 0650012
Citazione:
T. Takahashi et al., "Brain metastases of malignant melanoma showing unbalanced whole arm chromosomal translocations der (8;14) (q10; q10) and der (11;15) (q10; q10) in a Japanese patient", INTERN MED, 40(9), 2001, pp. 956-963

Abstract

Since malignant melanoma is a rare malignancy in Japan, little is known about the cytogenetic abnormalities in Japanese patients. We report a case ofmalignant melanoma showing complex chromosomal abnormalities. A 70-year-old woman was admitted to our hospital because of anorexia, delirium, and right hemiplegia. Cranial CT disclosed several metastatic brain tumors. Multiple subcutaneous and intra-abdominal metastases were also found. A diagnosisof metastatic malignant melanoma was made by biopsy of a subcutaneous tumor. Chromosomal analysis of the tumor cells disclosed complex karyotypic abnormalities including novel unbalanced whole arm translocations der (8; 14) (q10; q10) and der (11; 15) (q10; q10).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 16:46:45