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Titolo:
Potocytosis
Autore:
Mineo, C; Anderson, RGW;
Indirizzi:
Univ Texas, SW Med Ctr, Dept Cell Biol, Dallas, TX 75235 USA Univ Texas Dallas TX USA 75235 Ctr, Dept Cell Biol, Dallas, TX 75235 USA
Titolo Testata:
HISTOCHEMISTRY AND CELL BIOLOGY
fascicolo: 2, volume: 116, anno: 2001,
pagine: 109 - 118
SICI:
0948-6143(200108)116:2<109:P>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECEPTOR-MEDIATED ENDOCYTOSIS; CLATHRIN-COATED PITS; CONTINUOUS MICROVASCULAR ENDOTHELIUM; INTRACELLULAR CHOLESTEROL TRANSPORT; FILIPIN-STEROL COMPLEXES; LOW-DENSITY LIPOPROTEIN; RESISTANT CANCER-CELLS; GPI-ANCHORED PROTEINS; DEVELOPING T-TUBULES; GROWTH-FACTOR FGF-2;
Keywords:
potocytosis; caveolae; caveolin-1; endocytosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
117
Recensione:
Indirizzi per estratti:
Indirizzo: Anderson, RGW Univ Texas, SW Med Ctr, Dept Cell Biol, 5323 Harry Hines Blvd, Dallas, TX 75235 USA Univ Texas 5323 Harry Hines Blvd Dallas TX USA 75235 235 USA
Citazione:
C. Mineo e R.G.W. Anderson, "Potocytosis", HISTOCHEM C, 116(2), 2001, pp. 109-118

Abstract

Potocytosis represents a mechanism by which small and large molecules as well as macromolecular complexes are sequestered and transported by caveolae. Caveolae are flask-shaped plasma membrane specializations characterized by a filamentous coat consisting of caveolins that decorates the inside surface of each caveola membrane. They have endocytotic functions that differ from the clathrin-coated pit pathway. Ligands bound to receptors that are internalized by caveolae can be delivered to four different locations in the cell bypassing the lysosome and at least four different caveolae membrane traffic patterns during potocytosis can be distinguished. Hence, cells have two endocytic machines and each is designed to accomplish different tasks. This review provides a brief summary of the discovery of caveolae and of potocytosis, and focuses on recent discoveries of the unique endocytic capabilities of caveolae in a variety of different cells.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 14:56:40