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Titolo:
P-32 chromic phosphate radio synovectomy for chronic haemophilic synovitis
Autore:
Silva, M; Luck, JV; Siegel, ME;
Indirizzi:
Los Angeles Orthopaed Hosp, Los Angeles, CA 90007 USA Los Angeles Orthopaed Hosp Los Angeles CA USA 90007 Angeles, CA 90007 USA
Titolo Testata:
HAEMOPHILIA
, volume: 7, anno: 2001, supplemento:, 2
pagine: 40 - 49
SICI:
1351-8216(200107)7:<40:PCPRSF>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMOPHILIC ARTHROPATHY; RADIATION SYNOVECTOMY; FOLLOW-UP; SYNOVIORTHESIS; PATHOGENESIS; HEMARTHROSIS; ARTHRITIS;
Keywords:
haemophilia; chronic synovitis; radiosynovectomy; chromic phosphate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
62
Recensione:
Indirizzi per estratti:
Indirizzo: Luck, JV Los Angeles Orthopaed Hosp, 2400 S Flower St, Los Angeles, CA 90007 USA Los Angeles Orthopaed Hosp 2400 S Flower St Los Angeles CA USA 90007
Citazione:
M. Silva et al., "P-32 chromic phosphate radio synovectomy for chronic haemophilic synovitis", HAEMOPHILIA, 7, 2001, pp. 40-49

Abstract

The principal medical consequence of haemophilia is the development of arthropathy, initiated by a haemarthrosis giving rise to chronic synovitis. Traditional methods of synovectomy include open excision and arthroscopy eachof which require substantial amounts of clotting factor concentrate for several weeks, and in the case of open synovectomy, is often associated with loss of range of motion and arthrofibrosis. Radiosynovectomy, the intra-articular injection of low penetration radiocolloids, has been utilized outside the United States for over 20 years. Since 1988, our centre has performed170 radio-synovectomies utilizing P-32 chromic phosphate (P-32). This study reports results of 130 P-32 radiosyovectomies with an average follow-up of 36.5 months (6-140 months). For primary procedures, excellent and good results (haemarthrosis reduction from 75 to 100%) were obtained in 79.2% of cases at 6 months to 8 years. For repeat procedures a combination of excellent and good results were obtained in 62.4% of cases at 6 months to 3 years. Regression analysis showed no correlation between results and age or degree of arthropathy. Radiation was well contained within the joint. There wereno observed or identified complications. The procedure is highly cost effective in comparison to open surgical or arthroscopic synovectomy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 07:22:40