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Titolo:
Chemical synoviorthesis with osmic acid in haemophilia
Autore:
Ayral, X;
Indirizzi:
Univ Paris 05, Assistance Publ Hop Paris, Hop Cochin, Serv Rhumatol B, Paris, France Univ Paris 05 Paris France , Hop Cochin, Serv Rhumatol B, Paris, France
Titolo Testata:
HAEMOPHILIA
, volume: 7, anno: 2001, supplemento:, 2
pagine: 20 - 25
SICI:
1351-8216(200107)7:<20:CSWOAI>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYNOVECTOMY; KNEE;
Keywords:
chemical synoviorthesis; osmic acid; haemophilia; rheumatoid arthritis; synovitis; cartilage;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Ayral, X Serv Rhumatol B, 27 Rue Faubourg St Jacques, F-75679 Paris 14, France Serv Rhumatol B 27 Rue Faubourg St Jacques Paris France 14 rance
Citazione:
X. Ayral, "Chemical synoviorthesis with osmic acid in haemophilia", HAEMOPHILIA, 7, 2001, pp. 20-25

Abstract

Based on previous experience in inflammatory arthritis, a small number of open studies have evaluated the usefulness of chemical synoviorthesis with osmic acid in haemophilia, with various assessment criteria and a wide range of follow-up periods. Based on these studies, the efficacy of osmic acid seems modest, with 30-44% of good clinical and radiological results, but with fair or poor clinical results in other patients with a possible deleterious effect on cartilage. Osmic acid was found inferior to Yttrium-90 in oneretrospective study. Synoviorthesis with osmic acid seems particularly indicated in haemophilic arthritis with no or mild radiological deterioration in children between 8 and 15 years of age. However, prospective randomized studies are clearly required to evaluate the symptomatic and structural effects of chemical and radioactive synoviorthesis in haemophilic arthritis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 23:14:54