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Titolo:
Neuroendocrine aspects of aging in women
Autore:
Hall, JE; Gill, S;
Indirizzi:
Massachusetts Gen Hosp, Reprod Endocrine Unit, Dept Med, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 Dept Med, Boston, MA 02114 USA
Titolo Testata:
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
fascicolo: 3, volume: 30, anno: 2001,
pagine: 631 -
SICI:
0889-8529(200109)30:3<631:NAOAIW>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
GONADOTROPIN-RELEASING-HORMONE; FOLLICLE-STIMULATING-HORMONE; FREE ALPHA-SUBUNIT; PITUITARY-OVARIAN FUNCTION; LUTEINIZING-HORMONE; POSTMENOPAUSAL WOMEN; GENE-EXPRESSION; LH-SECRETION; MENOPAUSAL TRANSITION; HYPOTHALAMIC FUNCTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
81
Recensione:
Indirizzi per estratti:
Indirizzo: Hall, JE Massachusetts Gen Hosp, Reprod Endocrine Unit, Dept Med, BHX-5,55Fruit St, Boston, MA 02114 USA Massachusetts Gen Hosp BHX-5,55 Fruit St Boston MA USA 02114 USA
Citazione:
J.E. Hall e S. Gill, "Neuroendocrine aspects of aging in women", END METAB C, 30(3), 2001, pp. 631

Abstract

Recent evidence indicates that age-related neuroendocrine changes occur inwomen that are independent of those caused by the loss of ovarian feedbackaccompanying menopause. Studies suggest that both hypothalamic and pituitary changes contribute to the decrease in gonadotropin secretion that occurswith aging. The response to estrogen-negative feedback at the hypothalamusis preserved with aging, whereas the response to estrogen-positive feedback may decrease with aging, although this has not been fully investigated inwomen. The information to be gained from ongoing studies of the effects ofaging on the hypothalamic-pituitary axis will not only provide insights into the process of menopause, but will also contribute to our understanding of general mechanisms underlying the age-related deterioration of other neuroendocrine systems.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 10:48:17