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Titolo:
Therapeutic drug monitoring of psychotropic medications
Autore:
Mitchell, PB;
Indirizzi:
Univ New S Wales, Sch Psychiat, Kensington, NSW 2033, Australia Univ New SWales Kensington NSW Australia 2033 ngton, NSW 2033, Australia
Titolo Testata:
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
, volume: 52, anno: 2001, supplemento:, 1
pagine: 45S - 54S
SICI:
0306-5251(2001)52:<45S:TDMOPM>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERUM LITHIUM LEVELS; PERFORMANCE LIQUID-CHROMATOGRAPHY; REFRACTORY SCHIZOPHRENIC-PATIENTS; PLASMA CLOZAPINE CONCENTRATIONS; SEROTONIN REUPTAKE INHIBITORS; MANIC-DEPRESSIVE DISORDER; SOLID-PHASE EXTRACTION; CLINICAL-RESPONSE; BIPOLAR DISORDER; PHARMACOKINETIC PARAMETERS;
Keywords:
TDM; therapeutic drug monitoring; psychotropic; lithium; antidepressants; antipsychotics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
98
Recensione:
Indirizzi per estratti:
Indirizzo: Mitchell, PB Prince Wales Hosp, Mood Disorders Unit, Randwick, NSW 2031, Australia Prince Wales Hosp Randwick NSW Australia 2031 031, Australia
Citazione:
P.B. Mitchell, "Therapeutic drug monitoring of psychotropic medications", BR J CL PH, 52, 2001, pp. 45S-54S

Abstract

Therapeutic drug monitoring (TDM) of a number of psychotropic medications has proven to be of value, enabling minimization of the limitations of considerable genetic variability in their metabolism and the high rates of poorcompliance with many psychiatric disorders. Therapeutic ranges have been established for lithium, some of the tricyclic antidepressants, and clozapine. TDM has also been shown to be useful in avoiding toxicity (as many psychotropics have narrow therapeutic indices), particularly that due to interactions with other compounds.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/11/19 alle ore 02:26:52