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Titolo:
Questionnaire-based assessment of pelvic organ dysfunction in Parkinson's disease
Autore:
Sakakibara, R; Shinotoh, H; Uchiyama, T; Sakuma, M; Kashiwado, M; Yoshiyama, M; Hattori, T;
Indirizzi:
Chiba Univ, Sch Med, Dept Neurol, Chuo Ku, Chiba 2608670, Japan Chiba Univ Chiba Japan 2608670 ept Neurol, Chuo Ku, Chiba 2608670, Japan Kashiwado Mem Fund, Chuo Ku, Chiba 2600854, Japan Kashiwado Mem Fund Chiba Japan 2600854 nd, Chuo Ku, Chiba 2600854, Japan
Titolo Testata:
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL
fascicolo: 1-2, volume: 92, anno: 2001,
pagine: 76 - 85
SICI:
1566-0702(20010917)92:1-2<76:QAOPOD>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLE SYSTEM ATROPHY; URINARY-INCONTINENCE; VOIDING DYSFUNCTION; ANORECTAL FUNCTION; CLINICAL-FEATURES; SEXUAL FUNCTION; AGE; APOMORPHINE; PREVALENCE; SYMPTOMS;
Keywords:
Parkinson's disease; pelvic organ dysfunction; bladder dysfunction; bowel dysfunction; sexual dysfunction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Sakakibara, R Chiba Univ, Sch Med, Dept Neurol, Chuo Ku, 1-8-1 Inohana, Chiba 2608670, Japan Chiba Univ 1-8-1 Inohana Chiba Japan 2608670 2608670, Japan
Citazione:
R. Sakakibara et al., "Questionnaire-based assessment of pelvic organ dysfunction in Parkinson's disease", AUTON NEURO, 92(1-2), 2001, pp. 76-85

Abstract

Although patients with Parkinson's disease (PD) experience pelvic organ dysfunction of the urinary bladder, bowel and genital organs, an accurate incidence of the dysfunction and its characteristics have yet to be ascertained. We devised a detailed questionnaire on these three pelvic organ functions in PD patients and control subjects, in our search for a hallmark that would distinguish between the two groups. The PD group comprised 115 patients; 52 men and 63 women, age range 35-69 (average 59) years old, average duration of illness 6 years, median Hoehn and Yahr stage 3. All were taking levodopa with/without dopamine agonists. The control group comprised 391 localindividuals who were undergoing an annual health survey; 271 men and 120 women, age range 30-69 (average 48) years old. The questionnaire had three parts: bladder (nine questions), bowel (four questions); and sexual (three questions for women, five for men) function. Each question was scored from 0(none) to 3 (severe) with an additional quality of life (QOL) index scoredfrom 0 (satisfied) to 3 (extremely dissatisfied). The completion rate was 100% for bladder and bowel functions, whereas for sexual function, it was 95% (control) and 88% (PD) for men and 82% (control) and 60% (PD) for women. As compared with the control group, the frequency of dysfunction in the PDgroup was significantly higher for-urinary urgency (women 42%, men 54%), daytime frequency (28%, 16%), nighttime frequency (53%, 63%), urgency incontinence (25%, 28%), retardation (44% of men), prolongation/poor stream (men 70%), straining (women 28%); constipation (63%, 69%); difficulty in expulsion (men 57%), diarrhea (men 21%); decrease in libido (84%, 83%), decrease in sexual intercourse (55%, 88%), decrease in orgasm (men 87%), and in men, decreases in erection (79%) and ejaculation (79%). The QOL index for the PDpatients was significantly higher for bladder (27%, 28%) and bowel (46%, 59%) but not for sexual dysfunction, despite the group's high prevalence of sexual dysfunction. In the PD patients, fecal incontinence was. associated with urinary incontinence. Stress urinary incontinence and a decrease in libido were more common in women than in men. Bladder and bowel dysfunction, but not sexual dysfunction increased with the Hoehn and Yahr stage. Sexual dysfunction, but neither bladder nor bowel dysfunction, increased with age. Patients taking levodopa and bromocriptine more frequently had bladder (voiding phase) dysfunction than those taking levodopa only. The findings showthat bladder, bowel and sexual dysfunction are all prominent in patients with PD. Amelioration of pelvic organ dysfunction, particularly bowel dysfunction which most affects the quality of life, therefore should be a primarytarget in the treatment of patients with PD. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/06/20 alle ore 08:58:03