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Titolo:
Two new point mutations at A2062 associated with resistance to 16-memberedmacrolide antibiotics in mutant strains of Mycoplasma hominis
Autore:
Furneri, PM; Rappazzo, G; Musumarra, MP; Di Pietro, P; Catania, LS; Roccasalva, LS;
Indirizzi:
Univ Catania, Dipartimento Sci Microbiol & Sci Ginecol, I-95124 Catania, Italy Univ Catania Catania Italy I-95124 & Sci Ginecol, I-95124 Catania, Italy Univ Catania, Dipartimento Biol Anim, Catania, Italy Univ Catania Catania Italy ania, Dipartimento Biol Anim, Catania, Italy
Titolo Testata:
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
fascicolo: 10, volume: 45, anno: 2001,
pagine: 2958 - 2960
SICI:
0066-4804(200110)45:10<2958:TNPMAA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
23S RIBOSOMAL-RNA; PEPTIDYL TRANSFERASE CENTER; ERYTHROMYCIN RESISTANCE; ANTIMICROBIAL AGENTS; GENETIC-BASIS; CHLORAMPHENICOL; PNEUMONIAE; SUSCEPTIBILITY; BINDING; DOMAIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Furneri, PM Univ Catania, Dipartimento Sci Microbiol & Sci Ginecol, Via Androne 81, I-95124 Catania, Italy Univ Catania Via Androne 81 Catania ItalyI-95124 ania, Italy
Citazione:
P.M. Furneri et al., "Two new point mutations at A2062 associated with resistance to 16-memberedmacrolide antibiotics in mutant strains of Mycoplasma hominis", ANTIM AG CH, 45(10), 2001, pp. 2958-2960

Abstract

We describe two mutants of Mycoplasma hominis PG-21 which show resistance to 16-membered macrolides but susceptibility to lincosamides, obtained by in vitro exposure to increasing doses of josamycin. The 23S rRNA gene showedthat each had a mutation (A2062G and A2062T) corresponding to nucleotide 2062 in Escherichia coli, which was associated with the acquired phenotype.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 13:13:04