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Titolo:
Hypertension treatment patterns in American indians: The strong heart study
Autore:
Hayslett, JA; Eichner, JE; Yeh, JLL; Wang, WY; Henderson, J; Devereux, RB; Welty, TK; Fabsitz, RR; Howard, BV; Lee, ET;
Indirizzi:
Univ Oklahoma, Hlth Sci Ctr, Ctr Amer Indian Hlth Res, Coll Publ Hlth, Oklahoma City, OK 73190 USA Univ Oklahoma Oklahoma City OK USA 73190 lth, Oklahoma City, OK 73190 USA Aberdeen Area Tribal Chairmens Hlth Board, Rapid City, SD USA Aberdeen Area Tribal Chairmens Hlth Board Rapid City SD USA City, SD USA Cornell Univ, Weill Med Coll, New York, NY 10021 USA Cornell Univ New York NY USA 10021 Weill Med Coll, New York, NY 10021 USA NHLBI, Epidemiol & Biometry Program, Bethesda, MD 20892 USA NHLBI Bethesda MD USA 20892 ol & Biometry Program, Bethesda, MD 20892 USA MedStar Res Inst, Washington, DC USA MedStar Res Inst Washington DC USAMedStar Res Inst, Washington, DC USA
Titolo Testata:
AMERICAN JOURNAL OF HYPERTENSION
fascicolo: 9, volume: 14, anno: 2001,
parte:, 1
pagine: 950 - 956
SICI:
0895-7061(200109)14:9<950:HTPIAI>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMBULATORY CARE DATA; AGED 45-74 YEARS; CARDIOVASCULAR-DISEASE; CLINICAL HYPERTENSION; NATIVE-AMERICANS; ALASKA NATIVES; POPULATIONS; PROTEINURIA; PREVALENCE; RATES;
Keywords:
hypertension; epidemiology; Indians; North American; drug therapy; combination; diabetes mellitus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Eichner, JE Univ Oklahoma, Hlth Sci Ctr, Ctr Amer Indian Hlth Res, Coll Publ Hlth, POB26901, Oklahoma City, OK 73190 USA Univ Oklahoma POB 26901 Oklahoma City OK USA 73190 K 73190 USA
Citazione:
J.A. Hayslett et al., "Hypertension treatment patterns in American indians: The strong heart study", AM J HYPERT, 14(9), 2001, pp. 950-956

Abstract

Pharmacologic treatment patterns for hypertensive American Indians from 13communities in Arizona, Oklahoma, South Dakota, and North Dakota were assessed. Participants (2254 women and 1384 men, aged 48 to 79 years) completeda clinical examination between July 1993 and December 1995. The mean of two blood pressure (BP) measurements and detailed medication histories were obtained. The observed prevalence of hypertension was 46.7% (n = 1698). In participants taking antihypertensive medications (n = 1114), four principal drug classes were evaluated: diuretics, calcium channel blocking agents, beta -blocking agents, and angiotensin-converting enzyme (ACE) inhibitors. Among treated hypertensive participants, 71.4%, 24.6%, and 4.0% received one,two, and three medications, respectively. Among single drug regimens, ACE inhibitors (n = 340) were used most often (49.4%), with calcium channel blocking agents and diuretics accounting for 24.2% and 19.9%, respectively. Although multiple drug class therapies varied, the combination of a diuretic and ACE inhibitor (n = 120) accounted for 47.4% of dual therapy use. Hypertension control (SBP < 140 mm Hg, DBP < 90 mm Hg) rates were highest for those on dual therapies (65.4%), followed by participants on single (53.8%) and triple (43.6%) therapies. Among monotherapies, diuretics exhibited the best overall hypertension control rate in both diabetics (63.0%) and nondiabetics (68.0%), versus 47% to 61% for other remaining agents. The frequent use of ACE inhibitors, used singly or in combination, reflects the high prevalence of diabetes among American Indians. ACE inhibitors, combined with diuretics, were particularly useful in achieving BP control in this population. Am J Hypertens 2001:14:950-956 (C) 2001 American Journal of Hypertension,Ltd.

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Documento generato il 03/04/20 alle ore 20:28:42