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Titolo:
Respiratory symptoms at age 8 years in a cohort of very low birth weight children
Autore:
Palta, M; Sadek-Badawi, M; Sheehy, M; Albanese, A; Weinstein, M; McGuinness, G; Peters, ME;
Indirizzi:
Univ Wisconsin, Sch Med, Dept Prevent Med, Madison, WI 53705 USA Univ Wisconsin Madison WI USA 53705 pt Prevent Med, Madison, WI 53705 USA Univ Wisconsin, Sch Med, Dept Biostat & Med Informat, Madison, WI USA UnivWisconsin Madison WI USA pt Biostat & Med Informat, Madison, WI USA Univ Wisconsin, Dept Stat, Coll Letters & Sci, Madison, WI 53706 USA Univ Wisconsin Madison WI USA 53706 Letters & Sci, Madison, WI 53706 USA Univ Wisconsin, Sch Med, Dept Pediat, Madison, WI USA Univ Wisconsin Madison WI USA sin, Sch Med, Dept Pediat, Madison, WI USA St Marys Hosp, Dept Neonatol, Madison, WI USA St Marys Hosp Madison WI USA Marys Hosp, Dept Neonatol, Madison, WI USA Univ Iowa, Coll Med, Dept Pediat, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 ed, Dept Pediat, Iowa City, IA 52242 USA Univ Wisconsin, Sch Med, Dept Radiol, Madison, WI USA Univ Wisconsin Madison WI USA sin, Sch Med, Dept Radiol, Madison, WI USA
Titolo Testata:
AMERICAN JOURNAL OF EPIDEMIOLOGY
fascicolo: 6, volume: 154, anno: 2001,
pagine: 521 - 529
SICI:
0002-9262(20010915)154:6<521:RSAA8Y>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUNG-FUNCTION; BRONCHIAL HYPERRESPONSIVENESS; RISK-FACTORS; ASTHMA; PREVALENCE; CHILDHOOD; INFANTS; DISEASE; SURFACTANT; VALIDATION;
Keywords:
asthma; bronchopulmonary dysplasia; infant, very low birth weight; intensive care, neonatal; lung diseases, obstructive; outcome assessment (health care); pulmonary surfactants; respiratory sounds;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Palta, M Univ Wisconsin, Sch Med, Dept Prevent Med, 610 Walnut St, Madison, WI 53705 USA Univ Wisconsin 610 Walnut St Madison WI USA 53705 n, WI 53705 USA
Citazione:
M. Palta et al., "Respiratory symptoms at age 8 years in a cohort of very low birth weight children", AM J EPIDEM, 154(6), 2001, pp. 521-529

Abstract

The childhood respiratory consequences of very low birth weight (birth weight less than or equal to1,500 g) are incompletely understood, especially since the introduction of recent changes in neonatal care. To assess prevalence, trends, and risk factors for respiratory symptoms, the authors followed to age 8 years a cohort of 384 very low birth weight children from six regional neonatal intensive care units in Wisconsin and Iowa who were born between August 1, 1988, and June 30, 1991. A control group of 154 Wisconsin schoolchildren was also assembled. Respiratory symptoms in the past 12 months and history of asthma ("asthma ever") were reported by parents on a questionnaire used in the International Study of Asthma and Allergies in Childhood (ISAAC). Control group prevalence resembled ISAAC prevalence worldwide and in Canada, but respiratory symptoms were twice as common among very low birth weight children. With advent of the availability of pulmonary surfactants, the prevalence of wheezing at age 8 decreased from 50% to 16% (p = 0.002) among children with bronchopulmonary dysplasia, but it increased from 14% to 38% among those with milder neonatal respiratory disease. Bronchopulmonary dysplasia, family history of asthma, smoking in the household, and patent ductus arteriosus were predictive of wheezing in the previous 12 months. Antenatal steroid therapy had a borderline-significant protective association with wheezing (odds ratio = 0.56, 95% confidence interval: 0.29, 1.1). There were interaction effects between several of the predictors.

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Documento generato il 27/11/20 alle ore 02:11:07