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Titolo:
Health problems in adolescents with alcohol use disorders: Self-report, liver injury, and physical examination findings and correlates
Autore:
Clark, DB; Lynch, KG; Donovan, JE; Block, GD;
Indirizzi:
Western Psychiat Inst & Clin, Pittsburgh Adolescent Alcohol Res Ctr, Pittsburgh, PA 15213 USA Western Psychiat Inst & Clin Pittsburgh PA USA 15213 sburgh, PA 15213 USA Univ Pittsburgh, Sch Med, Dept Surg, Pittsburgh, PA USA Univ Pittsburgh Pittsburgh PA USA Sch Med, Dept Surg, Pittsburgh, PA USA
Titolo Testata:
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
fascicolo: 9, volume: 25, anno: 2001,
pagine: 1350 - 1359
SICI:
0145-6008(200109)25:9<1350:HPIAWA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
GAMMA-GLUTAMYL-TRANSFERASE; SUBSTANCE USE DISORDERS; GENDER DIFFERENCES; DSM-IV; PSYCHIATRIC COMORBIDITY; HIGH-SCHOOL; DRUG-USE; PSYCHOPATHOLOGY; DEPENDENCE; ABUSE;
Keywords:
adolescents; health; alcohol use disorders;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
63
Recensione:
Indirizzi per estratti:
Indirizzo: Clark, DB Western Psychiat Inst & Clin, Pittsburgh Adolescent Alcohol Res Ctr, 3811 Ohara St, Pittsburgh, PA 15213 USA Western Psychiat Inst & Clin 3811 Ohara St Pittsburgh PA USA 15213
Citazione:
D.B. Clark et al., "Health problems in adolescents with alcohol use disorders: Self-report, liver injury, and physical examination findings and correlates", ALC CLIN EX, 25(9), 2001, pp. 1350-1359

Abstract

Background: Although adolescent alcohol consumption has been found to be positively correlated with self-reported health problems, few studies have examined other health indicators. This study compared adolescents with alcohol use disorders (AUDs) and a community reference group on self-reported health problems, serum liver enzymes, and physical examination findings. The relevance of negative emotionality to understanding these health problems was also investigated. Methods: The subjects were adolescents with AUDs recruited from clinical programs and classified as having DSM-IV alcohol dependence (n = 71) or alcohol abuse (n = 57) and reference adolescents without AUDs recruited from community sources (n = 131). The assessment of health status included self-reported health problems in 15 areas; serum liver enzyme assays, including gamma -glutamyl transpeptidase, alanine aminotransferase, and aspartate aminotransferase; and physical examination findings. Negative emotionality was determined by systematically combining scores from the Hamilton Anxiety Rating Scale, the Beck Depression Inventory, the Child Behavior Checklist, and the Multidimensional Personality Questionnaire. Results: Adolescent AUDs were associated with more self-reported health problems, higher gamma -glutamyl transpeptidase and alanine aminotransferase levels, and more physical examination abnormalities. Negative emotionality was highly correlated with self-reported health problems, mediated the relationship between AUDs and self-reported health problems, and was not correlated with serum liver enzyme levels or physical examination abnormalities. Conclusions: These results indicated that AUDs during adolescence were associated with health problems, including modest but demonstrable liver injury. Self-reported health problems were probably best understood, in this context, as a negative emotionality manifestation.

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Documento generato il 16/01/21 alle ore 06:33:51