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Titolo:
Introduction to Department of Defense Center for Prostate Disease ResearchMulticenter National Prostate Cancer Database, and analysis of changes in the PSA-era
Autore:
Sun, L; Gancarczyk, K; Paquette, EL; McLeod, DG; Kane, C; Kusuda, L; Lance, R; Herring, J; Foley, J; Baldwin, D; Bishoff, JT; Soderdahl, D; Wu, HY; Xu, L; Moul, JW;
Indirizzi:
Uniformed Serv Univ Hlth Sci, Dept Surg, Ctr Prostate Dis Res, Rockville, MD 20852 USA Uniformed Serv Univ Hlth Sci Rockville MD USA 20852 ckville, MD 20852 USA Walter Reed Army Med Ctr, Washington, DC 20307 USA Walter Reed Army Med Ctr Washington DC USA 20307 Washington, DC 20307 USA San Diego Naval Med Ctr, San Diego, CA USA San Diego Naval Med Ctr San Diego CA USA aval Med Ctr, San Diego, CA USA Portsmouth Naval Med Ctr, Portsmouth, Hants, England Portsmouth Naval Med Ctr Portsmouth Hants England smouth, Hants, England Madigan Army Med Ctr, Tacoma, WA 98431 USA Madigan Army Med Ctr Tacoma WAUSA 98431 my Med Ctr, Tacoma, WA 98431 USA Natl Naval Med Res Inst, Bethesda, MD USA Natl Naval Med Res Inst Bethesda MD USA l Med Res Inst, Bethesda, MD USA Brooke Army Med Ctr, Ft Sam Houston, TX 78234 USA Brooke Army Med Ctr Ft Sam Houston TX USA 78234 Sam Houston, TX 78234 USA Malcolm Grow Med Ctr, Andrews AFB, MD USA Malcolm Grow Med Ctr Andrews AFB MD USA row Med Ctr, Andrews AFB, MD USA Wilford Hall USAF Med Ctr, Lackland AFB, TX 78236 USA Wilford Hall USAF Med Ctr Lackland AFB TX USA 78236 and AFB, TX 78236 USA Eisenhower Army Med Ctr, Ft Gordon, GA USA Eisenhower Army Med Ctr Ft Gordon GA USA Army Med Ctr, Ft Gordon, GA USA
Titolo Testata:
UROLOGIC ONCOLOGY
fascicolo: 5, volume: 6, anno: 2001,
pagine: 203 - 209
SICI:
1078-1439(200109/10)6:5<203:ITDODC>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
RADICAL PROSTATECTOMY; PROGNOSTIC VARIABLES; CAPSURE DATABASE; TRENDS; MORTALITY; RATES;
Keywords:
prostate cancer; database; epidemiology; disease-free survival;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Moul, JW Uniformed Serv Univ Hlth Sci, Dept Surg, Ctr Prostate Dis Res, 1530 E Jefferson St, Rockville, MD 20852 USA Uniformed Serv Univ Hlth Sci 1530 E Jefferson St Rockville MD USA 20852
Citazione:
L. Sun et al., "Introduction to Department of Defense Center for Prostate Disease ResearchMulticenter National Prostate Cancer Database, and analysis of changes in the PSA-era", UROL ONCOL, 6(5), 2001, pp. 203-209

Abstract

The Center for Prostate Disease Research (CPDR) database was developed to standardize the clinical procedures for patients with carcinoma of the prostate (CaP), and support retrospective and prospective studies on CaP withinthe military health care system. METHODS: A set of clinical forms recording diagnosis, treatments, follow-up, and necropsy information for CaP management was developed. A relational database with about 500 data fields for recording CaP status, clinical intervention and outcome was developed and installed in nine military facilities. As a demonstration of utility, the agesat diagnosis and death from CaP over the past 15 years were analyzed. RESULTS: As of the end of November 2000, the database has archived 242,227 records on 11,637 men. The mean number of follow-up visits per patient is presently 8.45 (98,323 total follow-up visits). A greater than 50% reduction in prostate cancer mortality was demonstrated. Dead/alive ratio is 21.1%. Prostate cancer specific mortality represents 30.1% of the total death population. The mean age at diagnosis decreased from 68.0 years in 1991 to 64.7 in 1999 (p<0.05). The age at death increased from 68.8 years before 1986 to 78.0 in 2000 (p<0.01). Mean surviving months between diagnosis and death is increased from 33.2 months before 1986 to 108.2 in 2000 (p<0.01). CONCLUSION: The CPDR database is suitable for analyzing epidemiological features of CaP, treatment efficacy, and for monitoring the quality of life of CaP patients. CaP detection and outcome is significantly improved in our military health care beneficiaries since the introduction of PSA and increased public awareness. Our goal is to accrue 20,000 men and follow them for 20 years. (C) 2001 Elsevier Science, Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 08:34:08