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Titolo:
Complexity and non-linearity in shock research: Reductionism or synthesis?
Autore:
Neugebauer, EAM; Willy, C; Sauerland, S;
Indirizzi:
Univ Cologne, Dept Surg 2, Biochem & Expt Div, D-51109 Cologne, Germany Univ Cologne Cologne Germany D-51109 Expt Div, D-51109 Cologne, Germany Univ Zurich Hosp, Dept Surg, Zurich, Switzerland Univ Zurich Hosp ZurichSwitzerland osp, Dept Surg, Zurich, Switzerland
Titolo Testata:
SHOCK
fascicolo: 4, volume: 16, anno: 2001,
pagine: 252 - 258
SICI:
1073-2322(200110)16:4<252:CANISR>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEPTIC SHOCK; AARONS ROD; SEPSIS; THERAPIES;
Keywords:
complexity; reductionism; synthesis; (non-) linearity; causality; systems thinking;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Neugebauer, EAM Univ Cologne, Dept Surg 2, Biochem & Expt Div, Ostmerheimer Str 200, D-51109 Cologne, Germany Univ Cologne Ostmerheimer Str 200 Cologne Germany D-51109
Citazione:
E.A.M. Neugebauer et al., "Complexity and non-linearity in shock research: Reductionism or synthesis?", SHOCK, 16(4), 2001, pp. 252-258

Abstract

The various analytical techniques used to explain the many supposed mediators of sepsis and septic shock have outpaced the integrative approaches that simplify this complexity for the physiologist and the clinician. In this article we discuss the pros and cons of reductionism and its limitations inthe field of shock research and emphasize the need for synthesis research. Taking account of the historical development of natural science, we will discuss the question of how far a reductionist approach can help to explain biological phenomena and conclude that reductionism, although essential to the scientific process, reduces the evidence absurdity if exaggerated. The part is never the whole, and it is impossible to understand the whole through limited dissections of its parts. The understanding of complex systems requires approaches other than those of explanatory reductionism. We emphasize a different approach-systems thinking. Systems scientists are not interested in the underlying components; they describe and characterize complex relations. Other disciplines that use systems thinking should be studied. However, to follow the concept of synthesis, reductionists must describe the components of the system. Reductionism and synthesis are therefore the two sides of a coin. Professional synthesis research is a serious challenge in shock research.

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Documento generato il 26/01/20 alle ore 16:51:49