Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Neurofibromatosis type 1: A diagnostic mimicker at CT
Autore:
Fortman, BJ; Kuszyk, BS; Urban, BA; Fishman, EK;
Indirizzi:
Johns Hopkins Univ Hosp, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21287 USA Johns Hopkins Univ Hosp Baltimore MD USA 21287 i, Baltimore, MD 21287 USA
Titolo Testata:
RADIOGRAPHICS
fascicolo: 3, volume: 21, anno: 2001,
pagine: 601 - 612
SICI:
0271-5333(200105/06)21:3<601:NT1ADM>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
NERVE SHEATH TUMORS; PLEXIFORM NEUROFIBROMA; BENIGN; THORAX;
Keywords:
extremities; extremities, neoplasms; neurofibromatosis; neuroma; pelvic organs; pelvic organs, neoplasms; thorax; thorax, neoplasms;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Fishman, EK Johns Hopkins Univ Hosp, Russell H Morgan Dept Radiol & RadiolSci, 600 N Wolfe St, Baltimore, MD 21287 USA Johns Hopkins Univ Hosp 600 NWolfe St Baltimore MD USA 21287
Citazione:
B.J. Fortman et al., "Neurofibromatosis type 1: A diagnostic mimicker at CT", RADIOGRAPHI, 21(3), 2001, pp. 601-612

Abstract

Neurofibromatosis type 1 (NF1) is the most common of the phakomatoses and has a variety of localized or, more frequently, systemic manifestations throughout the thorax, abdomen, pelvis, and extremities. Classic computed tomographic (CT) findings in NF I with thoracic involvement include small, well-defined subcutaneous neurofibromas, focal thoracic scoliosis, posterior vertebral scalloping, enlarged neural foramina, and characteristic rib abnormalities due to bone dysplasia or erosion from adjacent neurofibromas. However, more atypical manifestations are occasionally seen, and magnetic resonance (MR) imaging can be useful in equivocal cases. NF1 with abdominopelvic involvement tends to arise in the retroperitoneal, mesenteric, and paraspinal regions; it may be quite extensive and therefore difficult to distinguish from adenopathy at CT. The multiplanar capabilities of MR imaging, particularly with T2 weighting, make this modality helpful in evaluating affectedpatients and making the diagnosis. The classic peripheral manifestations of NF1 include limb hemihypertrophy, pseudarthrosis, peripheral nerve neurofibromas, and subcutaneous common and plexiform neurofibromas. In some casesof NF1, imaging findings are inconclusive, and biopsy and subsequent pathologic analysis are required. Familiarity with the various manifestations ofNF1 in different anatomic locations is important in making the diagnosis and optimizing postdiagnostic treatment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:06:01