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Titolo:
Autism-related diseases: clinical analysis of 295 children with major development disorders
Autore:
Bodier, C; Lenoir, P; Malvy, J; Barthelemy, C; Wiss, M; Sauvage, D;
Indirizzi:
CHRU, Serv Univ Pedopsychiat, Tours, France CHRU Tours FranceCHRU, Serv Univ Pedopsychiat, Tours, France CHRU, Ctr Ressources Autisme, Tours, France CHRU Tours FranceCHRU, Ctr Ressources Autisme, Tours, France CHRU, Serv Univ Explorat Fonct & Neurophysiol Pedopsych, Unite INSERM 316,Tours, France CHRU Tours France europhysiol Pedopsych, Unite INSERM 316,Tours, France
Titolo Testata:
PRESSE MEDICALE
fascicolo: 24, volume: 30, anno: 2001,
parte:, 1
pagine: 1199 - 1203
SICI:
0755-4982(20010901)30:24<1199:ADCAO2>2.0.ZU;2-F
Fonte:
ISI
Lingua:
FRE
Soggetto:
INFANTILE-AUTISM; MEDICAL CONDITIONS; EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Bodier, C Hop Bretonneau, Serv Univ Pedopsychiat, F-37044 Tours 1, France Hop Bretonneau Tours France 1 sychiat, F-37044 Tours 1, France
Citazione:
C. Bodier et al., "Autism-related diseases: clinical analysis of 295 children with major development disorders", PRESSE MED, 30(24), 2001, pp. 1199-1203

Abstract

OBJECTIVE: Known since the first descriptions in 1943, diseases related toautism and associated disorders have incited a growing body of work. Both theoretical interrogations (what is the pathogenic role of autism?) and practical measures (management, screening) are implied. Nevertheless the frequency of autism-related disease has varied from 10 to 37% depending on the series reported. We studied the frequency of these factors in a population of children with major development disorders cared for at the Tours university hospital over a 39-month period. PATIENTS AND METHODS: We reviewed retrospectively the medial features of 295 children examined in our psychiatrics and neurophysiology unit for children at the Tours center for major development disorders (based on the DSM IV diagnostic criteria) between September 1995 and December 1998. We dividedthese factors into 4 categories: hereditary diseases, serious medical conditions, minimal physical disorders and ante-or perinatal antecedents. RESULTS: Among these 295 children, 26.5% had a proven or probable hereditary disease, 19% had a serious medical condition and 21.7% had minimal physical disorders. Among the children with a serious medical condition, 34.4% also had ante- or perinatal antecedents. Among the 33% without any medical factor, 77% also had ante- or perinatal antecedents. CONCLUSION: Our data point out the quantitative importance of medical factors associated with major development disorders. They imply a close pluridisciplinary collaboration between child psychiatrists, pediatricians and geneticians in order to identify these disorders and develop an integrated management scheme. On a more theoretical level, it appears possible to identify subgroups of children among such a population based on associated diseases and neuropsychological patterns. This dimension would be useful for research into the pathogenic mechanisms involved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 07:01:46