Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Risk factors for acute rejection in pediatric living related liver transplantation: The impact of HLA matching
Autore:
Sugawara, Y; Mizuta, K; Kawarasaki, H; Takayama, T; Imamura, H; Makuuchi, M;
Indirizzi:
Univ Tokyo, Grad Sch Med, Dept Surg,Liver Transplantat Team, Artificial Organ & Transplantat Div,Bunkyo Ku, Tokyo 1138655, Japan Univ Tokyo Tokyo Japan 1138655 antat Div,Bunkyo Ku, Tokyo 1138655, Japan
Titolo Testata:
LIVER TRANSPLANTATION
fascicolo: 9, volume: 7, anno: 2001,
pagine: 769 - 773
SICI:
1527-6465(200109)7:9<769:RFFARI>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALLOGRAFT-REJECTION; COMPATIBILITY; RECIPIENTS; HISTOCOMPATIBILITY; TRANSFUSION; SURVIVAL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Sugawara, Y Univ Tokyo, Grad Sch Med, Dept Surg,Liver Transplantat Team, Artificial Organ & Transplantat Div,Bunkyo Ku, 7-3-1 Hongo, Tokyo 1138655, Japan Univ Tokyo 7-3-1 Hongo Tokyo Japan 1138655 kyo 1138655, Japan
Citazione:
Y. Sugawara et al., "Risk factors for acute rejection in pediatric living related liver transplantation: The impact of HLA matching", LIVER TRANS, 7(9), 2001, pp. 769-773

Abstract

The influence of HLA compatibility on acute rejection in cadaveric liver transplantation is not clearly defined, and that in living related liver transplantation (LRLT) has only been poorly examined. Few studies have focusedsolely on a pediatric population. Fifty-eight cases of pediatric LRLT wereanalyzed. Patient and graft survival rates and postoperative complicationswere assessed. The relationship between the incidence of acute rejection and HLA matching and some preoperative and intraoperative transplant recipient factors, including age, preoperative aspartate aminotransferase level, total bilirubin level, prothrombin time, ascites, donor-recipient blood group type and sex match, donor age, surgical time, anhepatic phase duration, volume of blood loss, and graft weight to standard liver volume, was examined. Patients with HLA-A zero mismatching (P = .04) or a greater volume of blood loss per body weight (P = .004) had a significantly lower chance of rejection within 6 weeks after LRLT. Our results show that in LRLT, a graft from an HLA-A zero-mismatched donor may be advantageous because it provides alower chance of early acute rejection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/02/20 alle ore 11:47:19