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Titolo:
Liver fibrosis attributed to lipid lowering medications: two cases
Autore:
Punthakee, Z; Scully, LJ; Guindi, MM; Ooi, TC;
Indirizzi:
Univ Ottawa, Ottawa Hosp, Div Endocrinol & Metab, Ottawa, ON K1Y 4E9, Canada Univ Ottawa Ottawa ON Canada K1Y 4E9 & Metab, Ottawa, ON K1Y 4E9, Canada Univ Ottawa, Ottawa Hosp, Dept Med, Ottawa, ON K1Y 4E9, Canada Univ Ottawa Ottawa ON Canada K1Y 4E9 Dept Med, Ottawa, ON K1Y 4E9, Canada Univ Ottawa, Ottawa Hosp, Div Gastroenterol, Ottawa, ON K1Y 4E9, Canada Univ Ottawa Ottawa ON Canada K1Y 4E9 oenterol, Ottawa, ON K1Y 4E9, Canada Univ Ottawa, Ottawa Hosp, Dept Pathol & Lab Med, Ottawa, ON K1Y 4E9, Canada Univ Ottawa Ottawa ON Canada K1Y 4E9 Lab Med, Ottawa, ON K1Y 4E9, Canada
Titolo Testata:
JOURNAL OF INTERNAL MEDICINE
fascicolo: 3, volume: 250, anno: 2001,
pagine: 249 - 254
SICI:
0954-6820(200109)250:3<249:LFATLL>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SIMVASTATINE-INDUCED HEPATITIS; CHRONIC ACTIVE HEPATITIS;
Keywords:
adverse effects; anticholesteremic agents; fibric acid derivatives; fibrosis; HMG-CoA reductase inhibitors; liver diseases;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Ooi, TC Univ Ottawa, Ottawa Hosp, Div Endocrinol & Metab, Civic Campus,1053 Carling Ave, Ottawa, ON K1Y 4E9, Canada Univ Ottawa Civic Campus,1053 Carling Ave Ottawa ON Canada K1Y 4E9
Citazione:
Z. Punthakee et al., "Liver fibrosis attributed to lipid lowering medications: two cases", J INTERN M, 250(3), 2001, pp. 249-254

Abstract

We identified two cases of chronic active hepatitis with liver fibrosis induced by lipid lowering drugs of the statin and fibrate classes despite regular monitoring of transaminases. There are few reports of clinically significant hepatitis induced by these drugs and even fewer cases of fibrosis. Given the growing use of these drugs, there are implications for monitoring patients on long-term therapy for liver damage.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/05/20 alle ore 17:01:57