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Titolo:
Immunology and immunopathology of the male genital tract - Experimental models to investigate the pathology of antisperm antibodies: approaches and problems
Autore:
Clayton, R; Moore, H;
Indirizzi:
Univ Sheffield, Dept Mol Biol & Biotechnol, Sheffield S10 2UH, S Yorkshire, England Univ Sheffield Sheffield S Yorkshire England S10 2UH S Yorkshire, England Univ Sheffield, Dept Obstet & Gynaecol, Sheffield S10 2UH, S Yorkshire, England Univ Sheffield Sheffield S Yorkshire England S10 2UH S Yorkshire, England
Titolo Testata:
HUMAN REPRODUCTION UPDATE
fascicolo: 5, volume: 7, anno: 2001,
pagine: 457 - 459
SICI:
1355-4786(200109/10)7:5<457:IAIOTM>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASECTOMY REVERSAL; HUMAN SPERMATOZOA; SURFACE-ANTIGENS; INFERTILE MEN; VASOVASOSTOMY; FERTILITY; ASSAYS;
Keywords:
antisperm antibodies; proteomics; vasectomy; vasovasostomy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Moore, H Univ Sheffield, Dept Mol Biol & Biotechnol, Firth Court, Sheffield S10 2UH, S Yorkshire, England Univ Sheffield Firth Court Sheffield S Yorkshire England S10 2UH
Citazione:
R. Clayton e H. Moore, "Immunology and immunopathology of the male genital tract - Experimental models to investigate the pathology of antisperm antibodies: approaches and problems", HUM REP UPD, 7(5), 2001, pp. 457-459

Abstract

Antisperm antibodies (ASA) can interfere with sperm function and fertilization. But we still know relatively little about the specific mechanisms that elicit an auto-immune response and we have a poor appreciation of the profile of ASA that lead to antibody-mediated infertility in the male. This brief review explores some of the experimental models, the current approachesand the problems associated with investigations of ASA.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/06/20 alle ore 00:07:30