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Titolo:
Versatile stem cells, young and old. A review
Autore:
Eridani, S;
Indirizzi:
CNR, ITBI, Inst Adv Biomed Technol, Milan, Italy CNR Milan ItalyCNR, ITBI, Inst Adv Biomed Technol, Milan, Italy
Titolo Testata:
CYTOTECHNOLOGY
fascicolo: 2, volume: 35, anno: 2001,
pagine: 137 - 143
SICI:
0920-9069(2001)35:2<137:VSCYAO>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW; MAMMALIAN EMBRYO; GROWTH-FACTOR; SELF-RENEWAL; CORD-BLOOD; HUMAN CNS; IN-VIVO; TRANSPLANTATION; PROGENITORS; BRAIN;
Keywords:
cell culture; cell differentiation; cell transplantation; stem cells; transdifferentiation;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Eridani, S CNR, ITBI, Inst Adv Biomed Technol, Milan, Italy CNR Milan Italy ITBI, Inst Adv Biomed Technol, Milan, Italy
Citazione:
S. Eridani, "Versatile stem cells, young and old. A review", CYTOTECHNOL, 35(2), 2001, pp. 137-143

Abstract

Both embryonic and somatic stem cells have been studied in recent years with particular regard to their differentiation potential. In vitro studies allow a considerable amplification of such cells in culture as well as the induction of commitment in different directions under proper stimulating factors. Moreover, a surprising versatility has been discovered, which makes possible a `reprogramming' of stem cells into a lineage pathway which may becompletely different from the expected direction: for instance, a production of brain cells from blood progenitors has been obtained. It is thus possible to envisage methods of producing in culture sufficient amounts of stemcells, committed to a certain pathway, which can be transplanted in vivo to replace damaged tissues and organs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 10:53:10