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Titolo:
Pituitary adenylate cyclase activating peptide (PACAP) immunoreactivity inthe ureter of the duck
Autore:
Mirabella, N; Squillacioti, C; Germano, G; Varricchio, E; Paino, G;
Indirizzi:
Univ Naples Federico II, Dept Biol Struct Funct & Technol, I-80137 Naples,Italy Univ Naples Federico II Naples Italy I-80137 chnol, I-80137 Naples,Italy Univ Basilicata, Dept Anim Prod Sci, I-85100 Potenza, Italy Univ Basilicata Potenza Italy I-85100 m Prod Sci, I-85100 Potenza, Italy
Titolo Testata:
CELL AND TISSUE RESEARCH
fascicolo: 3, volume: 305, anno: 2001,
pagine: 341 - 349
SICI:
0302-766X(200109)305:3<341:PACAP(>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
VASOACTIVE INTESTINAL POLYPEPTIDE; CENTRAL-NERVOUS-SYSTEM; IMMUNOHISTOCHEMICAL LOCALIZATION; MOLECULAR-CLONING; GASTROINTESTINAL-TRACT; URINARY-BLADDER; RAT-BRAIN; EXPRESSION; NEURONS; NEUROPEPTIDE;
Keywords:
radioimmunoassay; urinary tract; vasoactive intestinal peptide (VIP); Campbell khaki ducks; Anas platyrhynchos (Aves);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
65
Recensione:
Indirizzi per estratti:
Indirizzo: Mirabella, N Univ Naples Federico II, Dept Biol Struct Funct & Technol, Via Vet 1, I-80137 Naples, Italy Univ Naples Federico II Via Vet 1 Naples Italy I-80137 Italy
Citazione:
N. Mirabella et al., "Pituitary adenylate cyclase activating peptide (PACAP) immunoreactivity inthe ureter of the duck", CELL TIS RE, 305(3), 2001, pp. 341-349

Abstract

The presence, distribution and colocalisation of pituitary adenylate cyclase activating peptide (PACAP) immunoreactivity have been studied in the duck ureter by using Western blot analysis, radioimmunoassays (RIA) and immunohistochemistry. The presence of both PACAP-38 and PACAP-27 was demonstrated, PACAP-38 being the predominant form. PACAP-immunoreactive fibres and neurons were found in all the ureteral layers. Double immunostaining showed that PACAP was-almost completely colocalised with vasoactive intestinal peptide (VIP). Moreover, PACAP was found in substance P (SP)-containing ureteral nerve fibres and in SP-containing dorsal root ganglion neurons. RIA performed on denervated ureters demonstrated that almost half of the ureteral PACAP was extrinsic in origin. These findings suggest that, in birds, PACAP hasa role in diverse nerve-mediated ureteral functions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 13:19:13