Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Adjuvant chemotherapy for large cell carcinoma with neuroendocrine features
Autore:
Iyoda, A; Hiroshima, K; Toyozaki, T; Haga, Y; Baba, M; Fujisawa, T; Ohwada, H;
Indirizzi:
Chiba Univ, Sch Med, Inst Pulm Canc Res,Div Pathol, Chuo Ku, Chiba 2608670, Japan Chiba Univ Chiba Japan 2608670 Div Pathol, Chuo Ku, Chiba 2608670, Japan Chiba Univ, Sch Med, Inst Pulm Canc Res, Div Surg, Chiba 2608670, Japan Chiba Univ Chiba Japan 2608670 Canc Res, Div Surg, Chiba 2608670, Japan
Titolo Testata:
CANCER
fascicolo: 5, volume: 92, anno: 2001,
pagine: 1108 - 1112
SICI:
0008-543X(20010901)92:5<1108:ACFLCC>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEURO-ENDOCRINE NEOPLASMS; LUNG-CANCER; SURVIVAL ANALYSIS; TUMORS; CISPLATIN; COMBINATION; CRITERIA; MARKERS;
Keywords:
large cell neuroendocrine carcinoma; large cell carcinoma with neuroendocrine; differentiation; large cell carcinoma with neuroendocrine morphology; adjuvant chemotherapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Iyoda, A Chiba Univ, Sch Med, Inst Pulm Canc Res,Div Pathol, Chuo Ku, 1-8-1 Inohana, Chiba 2608670, Japan Chiba Univ 1-8-1 Inohana Chiba Japan 2608670 hiba 2608670, Japan
Citazione:
A. Iyoda et al., "Adjuvant chemotherapy for large cell carcinoma with neuroendocrine features", CANCER, 92(5), 2001, pp. 1108-1112

Abstract

BACKGROUND. In 1999, the World Health Organization categorized large cell neuroendocrine carcinoma, large cell carcinoma with neuroendocrine differentiation, and large cell carcinoma with neuroendocrine morphology as a variant of large cell carcinoma. Patients with large cell carcinoma vith neuroendocrine features have poor prognoses, comparable to those for small cell lung carcinoma. Small cell lung carcinoma is sensitive to chemotherapy; however, it is still unclear whether large cell carcinoma with neuroendocrine features is responsive to adjuvant chemotherapy. METHODS. The authors analyzed 73 patients with large cell carcinoma with neuroendocrine features who underwent resection of the tumor and studied theeffect Chiba, Japan. of adjuvant chemotherapy for large cell carcinoma with neuroendocrine features. RESULTS. in patients with Stage I disease, the overall survival for patients with cer Research, Chiba University School of Medicine, adjuvant chemotherapy based on cisplatin, carboplatin, or cyclophosphamide, Chiba, Japan. which were used as standard chemotherapy for small cell lung carcinoma, weresignificantly higher than the overall survival for patients without adjuvant chemotherapy. In patients with Stage II, III, and IV disease, there was no significant difference between patients with adjuvant chemotherapy and without adjuvant chemotherapy. CONCLUSIONS. Adjuvant chemotherapy based on cisplatin, carboplatin, or cyclophosphamide prolongs survival of patients with large cell carcinoma vith neuroendocrine features in early stage. (C) 2001 American Cancer Society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 20:25:40