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Titolo:
Excitotoxic lesions of the pre- and parasubiculum disrupt object recognition and spatial memory processes
Autore:
Liu, P; Jarrard, LE; Bilkey, DK;
Indirizzi:
Univ Otago, Dept Psychol, Dunedin, New Zealand Univ Otago Dunedin New Zealand tago, Dept Psychol, Dunedin, New Zealand Univ Otago, Ctr Res Neurosci, Dunedin, New Zealand Univ Otago Dunedin New Zealand , Ctr Res Neurosci, Dunedin, New Zealand Washington & Lee Univ, Dept Psychol, Lexington, VA 24450 USA Washington & Lee Univ Lexington VA USA 24450 hol, Lexington, VA 24450 USA
Titolo Testata:
BEHAVIORAL NEUROSCIENCE
fascicolo: 1, volume: 115, anno: 2001,
pagine: 112 - 124
SICI:
0735-7044(200102)115:1<112:ELOTPA>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
FREELY MOVING RATS; HIPPOCAMPAL-FORMATION; ENTORHINAL CORTEX; PERIRHINAL CORTEX; RETROHIPPOCAMPAL LESIONS; PATH INTEGRATION; FIMBRIA-FORNIX; WORKING-MEMORY; DAMAGE; REGION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
50
Recensione:
Indirizzi per estratti:
Indirizzo: Bilkey, DK Univ Otago, Dept Psychol, POB 56, Dunedin, New Zealand Univ Otago POB 56 Dunedin New Zealand 6, Dunedin, New Zealand
Citazione:
P. Liu et al., "Excitotoxic lesions of the pre- and parasubiculum disrupt object recognition and spatial memory processes", BEHAV NEURO, 115(1), 2001, pp. 112-124

Abstract

Rats with bilateral ibotenic acid lesions centered on the pre- and parasubiculum and control rats were tested in a series of spatial memory and object recognition memory tasks, Lesioned rats were severely impaired relative to controls in both the reference and working memory versions of the water maze task and displayed a delay-dependent deficit in a delayed nonmatch to place procedure conducted in the T-maze. Lesioned rats also displayed reduced exploration in a novel environment, and performance was altered in an object recognition procedure as compared with the control group. These findings indicate that the pre- and parasubiculum plays an important role in the processing of both object recognition and spatial memory.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 03:03:57