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Titolo:
Perirhinal cortex and place-object conditional learning in the rat
Autore:
Bussey, TJ; Dias, R; Amin, E; Muir, JL; Aggleton, JP;
Indirizzi:
Cardiff Univ, Sch Psychol, Cardiff, S Glam, Wales Cardiff Univ Cardiff S Glam Wales v, Sch Psychol, Cardiff, S Glam, Wales
Titolo Testata:
BEHAVIORAL NEUROSCIENCE
fascicolo: 4, volume: 115, anno: 2001,
pagine: 776 - 785
SICI:
0735-7044(200108)115:4<776:PCAPCL>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULTIPLE MEMORY-SYSTEMS; FORNIX TRANSECTION; RECOGNITION MEMORY; NEUROTOXIC LESIONS; SPATIAL MEMORY; RHESUS-MONKEYS; AREA TE; PARAHIPPOCAMPAL CORTICES; VISUAL RECOGNITION; EPISODIC MEMORY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
55
Recensione:
Indirizzi per estratti:
Indirizzo: Bussey, TJ Univ Cambridge, Dept Expt Psychol, Downing St, Cambridge CB2 3EB, England Univ Cambridge Downing St Cambridge England CB2 3EB B, England
Citazione:
T.J. Bussey et al., "Perirhinal cortex and place-object conditional learning in the rat", BEHAV NEURO, 115(4), 2001, pp. 776-785

Abstract

The present study examined whether excitotoxic lesions of the perirhinal cortex can affect acquisition of a place-object conditional task in which object and spatial information must be integrated. Testing was carried out ina double Y-maze apparatus. in which rats learned a conditional rule of thetype, "In Place X, choose Object A, not Object B (A+ vs. B-); in Place Y, choose Object B, not Object A (A- vs. B+). " Perirhinal cortex lesions significantly impaired acquisition of this task while sparing performance of an allocentric spatial memory task performed in a radial arm maze. Perirhinal cortex lesions also had no apparent effect on a 1-pair object discrimination task performed in the double Y maze or on retention and acquisition of 4-pair concurrent discrimination problems performed in a computer-automated touch screen testing apparatus. The results suggest that, although the perirhinal cortex and hippocampus can be functionally dissociated, their normal mode of operation includes the integration of object and spatial information.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 00:14:27