Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Amygdala lesions block conditioned enhancement of the early component of the rat eyeblink reflex
Autore:
Choi, JS; Lindquist, DH; Brown, TH;
Indirizzi:
Yale Univ, Dept Psychol, New Haven, CT 06520 USA Yale Univ New Haven CT USA 06520 v, Dept Psychol, New Haven, CT 06520 USA Yale Univ, Dept Mol & Cellular Physiol, New Haven, CT 06520 USA Yale UnivNew Haven CT USA 06520 ellular Physiol, New Haven, CT 06520 USA Yale Univ, Interdepartmental Neurosci Program, New Haven, CT 06520 USA Yale Univ New Haven CT USA 06520 eurosci Program, New Haven, CT 06520 USA
Titolo Testata:
BEHAVIORAL NEUROSCIENCE
fascicolo: 4, volume: 115, anno: 2001,
pagine: 764 - 775
SICI:
0735-7044(200108)115:4<764:ALBCEO>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
FEAR-POTENTIATED STARTLE; NICTITATING-MEMBRANE RESPONSE; ORBICULARIS OCULI MOTONEURONS; EVOKED BLINK REFLEX; ACOUSTIC STARTLE; MUTANT MICE; CENTRAL NUCLEUS; RAPHE MAGNUS; PROJECTIONS; MODULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
93
Recensione:
Indirizzi per estratti:
Indirizzo: Brown, TH Yale Univ, Dept Psychol, 2 Hillhouse Ave, New Haven, CT 06520 USA Yale Univ 2 Hillhouse Ave New Haven CT USA 06520 n, CT 06520 USA
Citazione:
J.S. Choi et al., "Amygdala lesions block conditioned enhancement of the early component of the rat eyeblink reflex", BEHAV NEURO, 115(4), 2001, pp. 764-775

Abstract

A tone conditioned stimulus (CS) previously paired with a grid shock unconditioned stimulus (US) can greatly enhance the early electromyographic (EMG) component (R1) of the rat eyeblink reflex. The hypothesis that the central nucleus of the amygdala (ACe) is an essential part of the circuitry mediating conditioned R1 enhancement was tested. After bilateral ACe lesions (L)or a sham operation (S), rats received paired presentations of the CS and US (P) or explicitly unpaired CS and US presentations (U), resulting in 4 groups: P/S. P/L, U/S, and U/L. ACe lesions completely prevented conditionedR1 enhancement, which was only exhibited in Group P/S. In the latter group, the "preextinction" conditioned enhancement effect was roughly a 2-fold increase in the R1 magnitude. Circuit-level mechanisms are discussed. and some advantages of the eyeblink EMG response in this general conditioning paradigm are considered.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 16:13:27