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Titolo:
Are diabetics more susceptible to the health effects of airborne particles?
Autore:
Zanobetti, A; Schwartz, J;
Indirizzi:
Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Environm Epidemiol Program, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Epidemiol Program, Boston, MA 02115 USA
Titolo Testata:
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 5, volume: 164, anno: 2001,
pagine: 831 - 833
SICI:
1073-449X(20010901)164:5<831:ADMSTT>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARTICULATE AIR-POLLUTION; HEART-RATE-VARIABILITY; HOSPITAL ADMISSIONS; GLUCOSE-TOLERANCE; TERM EXPOSURE; TIME-SERIES; MORTALITY; ASSOCIATION; DISEASE; RISK;
Keywords:
particles; diabetes; air pollution; heart disease; PM10;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Zanobetti, A Harvard Univ, Sch Publ Hlth, Dept Environm Hlth, Environm Epidemiol Program, 665 Huntington Ave, Boston, MA 02115 USA Harvard Univ 665 Huntington Ave Boston MA USA 02115 02115 USA
Citazione:
A. Zanobetti e J. Schwartz, "Are diabetics more susceptible to the health effects of airborne particles?", AM J R CRIT, 164(5), 2001, pp. 831-833

Abstract

Convincing evidence now exists that particulate air pollution exacerbates heart and lung disease, leading to increased morbidity and mortality. The populations particularly susceptible to these exposures are still unclear. Recent work on potential mechanisms of action of particulate air pollution point to pathways also influenced by diabetes. We examined whether diabetes modified the effect of airborne particles by looking at the association of PM10 with hospital admissions for heart and lung disease in persons with orwithout diabetes as a comorbidity. In addition we stratified by age withinpersons with and without diabetes. We used Medicare data for Cook County, Illinois for the years 1988-1994, and found that a 10 mug/m(3) increase in PM10 was associated with a 2.01% (95% CI 1.40-2.62%) increase in admissionsfor heart disease with diabetes, but only a 0.94% (95% CI 0.61-1.28%) increase In persons without diabetes. Similar effect modification was not seen for lung diseases. When analyzing by age we found twice the PM10-associatedrisk for heart disease in diabetics than nondiabetics in both age groups. We found for pneumonia admissions that diabetes is an effect modifier in the younger age group, and for COPD in the older age group. We conclude that persons with diabetes are a susceptible population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:22:19