Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Temporal order and spatial memory in schizophrenia: a parametric study
Autore:
Dreher, JC; Banquet, JP; Allilaire, JF; Paillere-Martinot, ML; Dubois, B; Burnod, Y;
Indirizzi:
Univ Paris 06, INSERM, U483, Paris, France Univ Paris 06 Paris FranceUniv Paris 06, INSERM, U483, Paris, France Hop La Pitie Salpetriere, Adult Psychiat Sect, Paris, France Hop La Pitie Salpetriere Paris France dult Psychiat Sect, Paris, France Hop La Pitie Salpetriere, INSERM, U289, Paris, France Hop La Pitie Salpetriere Paris France iere, INSERM, U289, Paris, France
Titolo Testata:
SCHIZOPHRENIA RESEARCH
fascicolo: 2-3, volume: 51, anno: 2001,
pagine: 137 - 147
SICI:
0920-9964(20010901)51:2-3<137:TOASMI>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
DORSOLATERAL PREFRONTAL CORTEX; MONOZYGOTIC TWINS DISCORDANT; FIRST-EPISODE SCHIZOPHRENIA; WORKING-MEMORY; FRONTAL-LOBE; DOPAMINE-RECEPTORS; NEGATIVE SYMPTOMS; DEFICITS; DYSFUNCTION; PERFORMANCE;
Keywords:
frontal lobe; spatial working memory; executive processes; schizophrenia; encoding; retention; retrieval; rehearsal;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Dreher, JC NIMH, Unit Integrat Neuroimaging, Clin Brain Disorders Branch, Bldg 10,Room 4C-101,9000 Rockville Pike, Bethesda, MD 20892 USA NIMH Bldg 10,Room 4C-101,9000 Rockville Pike Bethesda MD USA 20892
Citazione:
J.C. Dreher et al., "Temporal order and spatial memory in schizophrenia: a parametric study", SCHIZOPHR R, 51(2-3), 2001, pp. 137-147

Abstract

Spatial working memory has been shown to be impaired in schizophrenia. In contrast, memory for temporal order has been poorly studied in patients with schizophrenia. The aim of this study was to compare and to further characterize spatial working memory and sequence reproduction deficits in patients with schizophrenia under stable medication by manipulating cues (pattern versus sequence), delay, set-size and response type in various recall and recognition tasks. This allowed us to dissociate processes as encoding, retention and retrieval and to compare the performance of patients with schizophrenia to the performance of patients with prefrontal lesions, who have been previously tested in the same tasks. Our results show that increase of the set-size and of the delay decreased performance of both groups, and that these factors had larger detrimental effects in patients with schizophreniathan in controls. Furthermore, comparison between tasks revealed retentionand retrieval deficits in schizophrenia. Finally, patients with schizophrenia showed impairments not only in recall but also in sequence recognition tasks with delay. This is in contrast to patients with prefrontal lesions, who have previously been shown to have intact recognition of sequences after a delay. These results suggest that the working memory deficit in schizophrenia cannot be restricted to a prefrontal dysfunction. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:45:07