Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Receptors and entry cofactors for retroviruses include single and multipletransmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins
Autore:
Overbaugh, J; Miller, AD; Eiden, MV;
Indirizzi:
Fred Hutchinson Canc Res Ctr, Div Human BIol, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr Seattle WA USA 98109 , Seattle, WA 98109 USA NIMH, Lab Cellular & Mol Regulat, Bethesda, MD 20892 USA NIMH Bethesda MDUSA 20892 Cellular & Mol Regulat, Bethesda, MD 20892 USA
Titolo Testata:
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
fascicolo: 3, volume: 65, anno: 2001,
pagine: 371 -
SICI:
1092-2172(200109)65:3<371:RAECFR>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; FELINE LEUKEMIA-VIRUS; AMINO-ACID TRANSPORTER; CELL-SURFACE RECEPTOR; ECOTROPIC MURINE RETROVIRUSES; GP120 ENVELOPE GLYCOPROTEIN; SARCOMA-ASSOCIATED VIRUS; MACROPHAGE-TROPIC HIV-1; N-LINKED GLYCOSYLATION; SPLEEN NECROSIS VIRUS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
200
Recensione:
Indirizzi per estratti:
Indirizzo: Overbaugh, J Fred Hutchinson Canc Res Ctr, Div Human BIol, 1100 Fairview Ave N,C3-168, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr 1100 Fairview Ave N,C3-168 Seattle WA USA 98109
Citazione:
J. Overbaugh et al., "Receptors and entry cofactors for retroviruses include single and multipletransmembrane-spanning proteins as well as newly described glycophosphatidylinositol-anchored and secreted proteins", MICRO M B R, 65(3), 2001, pp. 371

Abstract

In the past few years, many retrovirus receptors, coreceptors, and cofactors have been identified. These molecules are important for some aspects of viral entry, although in some cases it remains to be determined whether they are required for binding or postbinding stages in entry, such as fusion. There are certain common features to the molecules that many retroviruses use to gain entry into the cell. For example, the receptors for most mammalian oncoretroviruses are multiple membrane-spanning transport proteins. However, avian retroviruses use single-pass membrane proteins, and a sheep retrovirus uses a glycosylphosphatidylinositol-anchored molecule as its receptor. For some retroviruses, particularly the lentiviruses, two cell surface molecules are required for efficient entry. More recently, a soluble proteinthat is required for viral entry has been identified for a feline oncoretrovirus. In this review, we will focus on the various strategies used by mammalian retroviruses to gain entry into the cell. The choice of receptors will also be discussed in light of pressures that drive viral evolution and persistence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 23:59:43