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Titolo:
Intraoperative magnetic resonance imaging during transsphenoidal surgery
Autore:
Fahlbusch, R; Ganslandt, O; Buchfelder, M; Schott, W; Nimsky, C;
Indirizzi:
Univ Erlangen Nurnberg, Dept Neurosurg, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-91054 -91054 Erlangen, Germany
Titolo Testata:
JOURNAL OF NEUROSURGERY
fascicolo: 3, volume: 95, anno: 2001,
pagine: 381 - 390
SICI:
0022-3085(200109)95:3<381:IMRIDT>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOPPLER ULTRASONOGRAPHY; PITUITARY-TUMOR; NEUROSURGERY; RESECTION; EXPERIENCE; ULTRASOUND; SCANNER; SYSTEM; GLAND; MR;
Keywords:
pituitary adenoma; intraoperative magnetic resonance imaging; transsphenoidal surgery;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Nimsky, C Univ Erlangen Nurnberg, Dept Neurosurg, Schwabachanlage 6, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Schwabachanlage 6 Erlangen Germany D-91054
Citazione:
R. Fahlbusch et al., "Intraoperative magnetic resonance imaging during transsphenoidal surgery", J NEUROSURG, 95(3), 2001, pp. 381-390

Abstract

Object. The aim of this study was to evaluate whether intraoperative magnetic resonance (MR) imaging can increase the efficacy of transsphenoidal microsurgery, primarily in non-hormone-secreting intra- and suprasellar pituitary macroadenomas. Methods. Intraoperative imaging was performed using a 0.2-tesla MR imager,which was located in a specially designed operating room. The patient was placed supine on the sliding table of the MR imager, with the head placed near the 5-gauss line. A standard flexible coil was placed around the patient's forehead. Microsurgery was performed using MR-compatible instruments. Image acquisition was started after the sliding table had been moved into the center of the magnet. Coronal and sagittal T-1-weighted images each required over 8 minutes to acquire, and T-2-weighted images were obtained optionally. To assess the reliability of intraoperative evaluation of tumor resection, the intraoperative findings were compared with those on conventional postoperative 1.5-tesla MR images, which were obtained 2 to 3 months after surgery. Among 44 patients with large intra- and suprasellar pituitary adenomas that were mainly hormonally inactive, intraoperative MR imaging allowed an ultra-early evaluation of tumor resection in 73% of cases; such an evaluation is normally only possible 2 to 3 months after surgery. A second intraoperative examination of 24 patients for suspected tumor remnants led to additional resection in 15 patients (34%). Conclusions. Intraoperative MR imaging undoubtedly offers the option of a second look within the same surgical procedure if incomplete tumor resection is suspected. Thus, the rate of procedures during which complete tumor removal is achieved can be improved. Furthermore, additional treatments for those patients in whom tumor removal was incomplete can be planned at an early stage, namely just after surgery.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 11:54:54