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Titolo:
An introduction to quadrupole-time-of-flight mass spectrometry
Autore:
Chernushevich, IV; Loboda, AV; Thomson, BA;
Indirizzi:
MDS SCIEX, Concord, ON L4K 4V8, Canada MDS SCIEX Concord ON Canada L4K 4V8 DS SCIEX, Concord, ON L4K 4V8, Canada
Titolo Testata:
JOURNAL OF MASS SPECTROMETRY
fascicolo: 8, volume: 36, anno: 2001,
pagine: 849 - 865
SICI:
1076-5174(200108)36:8<849:AITQMS>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
ASSISTED-LASER-DESORPTION/IONIZATION; COLLISIONAL DAMPING INTERFACE; ELECTROSPRAY-IONIZATION; PROTEIN IDENTIFICATION; DESORPTION IONIZATION; ORTHOGONAL-INJECTION; PEPTIDE; IONS; BIOMOLECULES; EXTRACTION;
Keywords:
time-of-flight mass spectrometry; quadrupole mass spectrometry; collision-induced dissociation; electrospray; matrix-assisted laser desorption/ionization;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
59
Recensione:
Indirizzi per estratti:
Indirizzo: Chernushevich, IV MDS SCIEX, 71 4 Valley Dr, Concord, ON L4K 4V8, Canada MDS SCIEX 71 4 Valley Dr Concord ON Canada L4K 4V8 anada
Citazione:
I.V. Chernushevich et al., "An introduction to quadrupole-time-of-flight mass spectrometry", J MASS SPEC, 36(8), 2001, pp. 849-865

Abstract

A brief introduction is presented to the basic principles and application of a quadrupole-time-of-flight (TOF) tandem mass spectrometer. The main features of reflecting TOF instruments with orthogonal injection of ions are discussed. Their operation and performance are compared with those of triplequadrupoles with electrospray ionization and matrix-assisted laser desorption/ionization (MALDI) TOF mass spectrometers. Examples and recommendationsare provided for all major operational modes: mass spectrometry (MS) and tandem MS (MS/MS), precursor ion scans and studies of non-covalent complexes: Basic algorithms for liquid chromatography/MS/MS automation are discussedand illustrated by two applications. Copyright (C) 2001 John Wiley & Sons,Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 13:24:51