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Titolo:
Heavy metal detoxification in plants: Phytochelatin biosynthesis and function
Autore:
Cobbett, CS;
Indirizzi:
Univ Melbourne, Dept Genet, Melbourne, Vic 3010, Australia Univ MelbourneMelbourne Vic Australia 3010 elbourne, Vic 3010, Australia
Titolo Testata:
IUBMB LIFE
fascicolo: 3, volume: 51, anno: 2001,
pagine: 183 - 188
SICI:
1521-6543(200103)51:3<183:HMDIPP>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARABIDOPSIS-THALIANA; BINDING PEPTIDES; SCHIZOSACCHAROMYCES-POMBE; GLUTATHIONE-DEFICIENT; SENSITIVE MUTANTS; CADMIUM TOLERANCE; FISSION YEAST; SYNTHASE; GENES; TRANSPORT;
Keywords:
Arabidopsis; glutathione; heavy metal detoxification; phytochelatins;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Cobbett, CS Univ Melbourne, Dept Genet, Melbourne, Vic 3010, Australia Univ Melbourne Melbourne Vic Australia 3010 c 3010, Australia
Citazione:
C.S. Cobbett, "Heavy metal detoxification in plants: Phytochelatin biosynthesis and function", IUBMB LIFE, 51(3), 2001, pp. 183-188

Abstract

Phytochelatins (PCs) are a family of peptides important in the detoxification of heavy metals such as cadmium in plants and some microorganisms. PCs are synthesised enzymatically from glutathione. Molecular genetic studies, particularly in the yeast Schizosaccharomyces pombe and in the plant Arabidopsis thaliana, have identified a number of genes important in the biosynthesis or function of PCs. PC-deficient mutants of Arabidopsis have confirmedboth the role of glutathione as the substrate for PC biosynthesis and the role of PCs themselves in heavy metal detoxification in plants. PC synthasegenes have been identified in Arabidopsis and other plant species as well as in a number of animal species, suggesting PCs play a wider role in metaldetoxification than previously anticipated. PC synthesis is regulated at anumber of levels, most importantly through the activation of PC synthase by metal ions. This article reviews recent advances in our understanding of the biosynthesis and function of PCs in plants and other organisms.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 03:24:25