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Titolo:
Subtyping and antifungal susceptibilities of Candida spp. in the intensivecare unit of a Greek general hospital
Autore:
Kanellopoulou, M; Stamos, G; Petinnelli, I; Savala, M; Tzimogianni, A; Legakis, NJ; Foustoukou, M; Papafragas, E; Velegraki, A;
Indirizzi:
Univ Athens, Sch Med, Dept Microbiol, Mycol Reference Lab, GR-11527 Athens, Greece Univ Athens Athens Greece GR-11527 eference Lab, GR-11527 Athens, Greece Dist Gen Hosp Nikea, Dept Microbiol, Piraeus, Greece Dist Gen Hosp Nikea Piraeus Greece kea, Dept Microbiol, Piraeus, Greece
Titolo Testata:
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
fascicolo: 2, volume: 18, anno: 2001,
pagine: 179 - 183
SICI:
0924-8579(200108)18:2<179:SAASOC>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUTROPENIC PATIENTS; ORAL CANDIDIASIS; ALBICANS; FLUCONAZOLE; INFECTIONS; IDENTIFICATION; RESISTANCE; KARYOTYPE; AIDS;
Keywords:
Candida spp.; ICU; antifungal susceptibility; subtyping; PFGE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Velegraki, A Univ Athens, Sch Med, Dept Microbiol, Mycol Reference Lab, Mikras Asias 75-77, GR-11527 Athens, Greece Univ Athens Mikras Asias 75-77 Athens Greece GR-11527 Greece
Citazione:
M. Kanellopoulou et al., "Subtyping and antifungal susceptibilities of Candida spp. in the intensivecare unit of a Greek general hospital", INT J ANT A, 18(2), 2001, pp. 179-183

Abstract

This study identified the Candida spp., susceptibility to antifungal agents and the prevailing Candida albicans subtypes responsible for infections or colonization of 42 patients in the ICU over a 6-month period. Most isolates were C. albicans (66.1%) and Candida tropicalis (28.3%) all of which were susceptible in vitro to antifungal agents. Subtypes of the C. albicans isolates were identified by pulsed field gel electrophoresis Sfi I chromosomal digests. Two major C. albicans subtypes were identified, whereas subtype heterogeneity was found among strains of Candida glabrata and C. tropicalis. Sfi I PFGE restriction patterns were able to discriminate between sub-populations of C. albicans isolates, clustering them into distinct, epidemiologically congruous groups. (C) 2001 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 07:01:46