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Titolo:
The oxygenation variations related to prone positioning du ventilation: a clinical ring mechanical comparison between ARDS and non-ARDS hypoxemic patients
Autore:
Venet, C; Guyomarch, S; Migeot, C; Bertrand, M; Gery, P; Page, D; Vermesch, R; Bertrand, JC; Zeni, F;
Indirizzi:
CHRU St Etienne, Serv Reanimat Polyvalente, Hop Bellevue, F-42055 St Etienne Du Rouvray 2, France CHRU St Etienne St Etienne Du Rouvray France 2 enne Du Rouvray 2, France
Titolo Testata:
INTENSIVE CARE MEDICINE
fascicolo: 8, volume: 27, anno: 2001,
pagine: 1352 - 1359
SICI:
0342-4642(200108)27:8<1352:TOVRTP>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY-DISTRESS-SYNDROME; ACUTE LUNG INJURY; GAS-EXCHANGE; NITRIC-OXIDE; FAILURE;
Keywords:
ARDS; prone position; mechanical ventilation; clinical study;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Venet, C CHRU St Etienne, Serv Reanimat Polyvalente, Hop Bellevue, F-42055St Etienne Du Rouvray 2, France CHRU St Etienne St Etienne Du Rouvray France 2 ouvray 2, France
Citazione:
C. Venet et al., "The oxygenation variations related to prone positioning du ventilation: a clinical ring mechanical comparison between ARDS and non-ARDS hypoxemic patients", INTEN CAR M, 27(8), 2001, pp. 1352-1359

Abstract

Objectives: To compare, in clinical practice, the oxygenation variations related to prone positioning (PP) during mechanical ventilation in ARDS and non-ARDS hypoxemic patients. Design and setting: Prospective observational study of data on consecutivepatients treated with the same protocol in the intensive care unit (ICU) of a university hospital. Patients: From May 1996 to December 1998, 226 PP periods without adjunction of nitric oxide (NO) inhalation and/or almitrine bismesylate infusion, performed in 59 mechanically ventilated hypoxemic patients (arterial oxygen tension/fractional inspired oxygen (PaO2/FIO2) ratio < 300 mmHg) with no evidence of left ventricular failure. were included in this study. Measurements: Arterial blood gas was measured before the PP, at 1 h from the beginning of the PP, at the end of the PP and 1 It after returning to the supine position. Results: We analyzed 136 PP periods in 34 non-ARDS patients (60.2 %) and 90 in 25 ARDS patients. The PP was repeated and the duration of the PP periods was: 10.6 +/- 0.22 h. The PP during the mechanical ventilation appeared to be safe and well tolerated. A PaO2/FIO2 ratio improvement at the end of the PP period. occurred for 196 periods (86.7 %) with a mean PaO2/FIO2 ratio increase of +46.4 +/- 0.03 % at the end of the PP periods compared to thebaseline supine value. The PaO2/FIO2 ratio variations at 1 h after the start of the PP. at the end of the PP period and at 1 h after the return to supine were not different in ARDS or non-ARDS hypoxemic patients. The PaO2/FIO2 ratio improvement appeared to be more intense and more rapid in ARDS patients. Conclusions: In about 90 % of periods, PP improved the PaO2/FIO2 ratio in patients with ARDS as well as in hypoxemic patients with non-ARDS. Studies are necessary to determine the impact of PP on survival and the mechanical ventilation duration in ARDS or non-ARDS hypoxemic patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 19:44:24