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Titolo:
The 49a,f haplotype 11 is a new marker of the EU19 lineage that traces migrations from northern regions of the Black Sea
Autore:
Passarino, G; Semino, O; Magri, C; Al-Zahery, N; Benuzzi, G; Quintana-Murci, L; Andellnovic, S; Bullc-Jakus, F; Liu, AP; Arslan, A; Santachiara-Benerecetti, AS;
Indirizzi:
Univ Pavia, Dipartimento Genet & Microbiol, I-27100 Pavia, Italy Univ Pavia Pavia Italy I-27100 o Genet & Microbiol, I-27100 Pavia, Italy Univ Calabria, Dipartimento Biol Cellulare, Arcavacata Di Rende, Italy Univ Calabria Arcavacata Di Rende Italy are, Arcavacata Di Rende, Italy Univ Hosp Split, Dept Pathol, Split, Croatia Univ Hosp Split Split Croatia v Hosp Split, Dept Pathol, Split, Croatia Clin Hosp Ctr Osijek, Dept Pathol, Osijek, Croatia Clin Hosp Ctr Osijek Osijek Croatia sijek, Dept Pathol, Osijek, Croatia Univ Auckland, Fac Med & Hlth Sci, Auckland Canc Res Ctr, Auckland 1, New Zealand Univ Auckland Auckland New Zealand 1 nc Res Ctr, Auckland 1, New Zealand Selcuk Univ, Tip Fak, Tibbi Biyoloji Genet, Anabilim Dali, Konya, Turkey Selcuk Univ Konya Turkey i Biyoloji Genet, Anabilim Dali, Konya, Turkey
Titolo Testata:
HUMAN IMMUNOLOGY
fascicolo: 9, volume: 62, anno: 2001,
pagine: 922 - 932
SICI:
0198-8859(200109)62:9<922:T4H1IA>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN Y-CHROMOSOME; HUMAN-POPULATIONS; POLYMORPHISMS; EUROPE; MUTATION; AFRICA; ORIGIN; ASIA;
Keywords:
Y-chromosome polymorphisms; East Europe; Ukraine; migrations;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Santachiara-Benerecetti, AS Univ Pavia, Dipartimento Genet & Microbiol, Via Ferrata 1, I-27100 Pavia, Italy Univ Pavia Via Ferrata 1 Pavia Italy I-27100
Citazione:
G. Passarino et al., "The 49a,f haplotype 11 is a new marker of the EU19 lineage that traces migrations from northern regions of the Black Sea", HUMAN IMMUN, 62(9), 2001, pp. 922-932

Abstract

Previous studies on human Y-chromosome polymorphisms in the European populations highlighted the high frequency of the 49a,f/TaqI haplotype I I and of the Eu19 (M17) lineage in Eastern Europe. To better understand the originand the evolution of the Eu19, and its relationship with 49a,f Ht11, this study surveyed 2,235 individuals (mainly from Europe and the Middle East) for the 49a,f Ht I I and for many biallelic markers defining the Eu19 lineage. As previously described, the highest frequency of Eu19 was found in Eastern Europe. All the Eu19 Y-chromosomes turned out to be 49a,f Ht11 or its derivatives, the distribution of which suggests that the Eu19/49a,f Ht11 emerged in Ukraine, probably in a Palaeolithic population. Thereafter, the spread of this lineage toward Europe, Asia, and India occurred at different waves over a few thousands years. At present this seems to indicate the influence of the Ukraine Palaeolithic groups in the gene pool of modern populations. For the first time it is possible to make inferences about the evolution of some haplotypes of the 49a,f system. In spite of its unknown molecular base, this is one of the first most informative polymorphisms of the Y chromosome. Human Immunology 62, 922-932 (2001) (C) American Society for Histocompatibility and Immunogenetics, 2001. Published by Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/11/20 alle ore 22:30:27