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Titolo:
Fatty acid absorption in preterms on formulas with and without long-chain polyunsaturated fatty acids and in terms on formulas without these added
Autore:
Moya, M; Cortes, E; Juste, M; De Dios, JG; Vera, A;
Indirizzi:
Univ Miguel Hernandez, Dept Pediat, Hosp Univ San Juan, Alicante 03550, Spain Univ Miguel Hernandez Alicante Spain 03550 n Juan, Alicante 03550, Spain
Titolo Testata:
EUROPEAN JOURNAL OF CLINICAL NUTRITION
fascicolo: 9, volume: 55, anno: 2001,
pagine: 755 - 762
SICI:
0954-3007(200109)55:9<755:FAAIPO>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
RANDOMIZED CONTROLLED TRIAL; BIRTH-WEIGHT INFANTS; HUMAN-MILK; PALMITIC ACID; WHOLE-BODY; INTESTINAL-ABSORPTION; PREMATURE-INFANTS; ARACHIDONIC-ACID; MINERAL BALANCE; BREAST-MILK;
Keywords:
fatty acid absorption; full-term and preterm; DHA net retention; AA net retention;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Moya, M Univ Miguel Hernandez, Dept Pediat, Hosp Univ San Juan, Ctra Valencia S-N,Alicante 03550, Spain Univ Miguel Hernandez Ctra Valencia S-N Alicante Spain 03550 pain
Citazione:
M. Moya et al., "Fatty acid absorption in preterms on formulas with and without long-chain polyunsaturated fatty acids and in terms on formulas without these added", EUR J CL N, 55(9), 2001, pp. 755-762

Abstract

Background/objective: Long chain polyunsaturated fatty acids have beneficial effects in preterm neurophysiological development and are semi-essential. Their levels and variation in plasma and red cells in term and preterms are better known than their intestinal absorption. In this paper the absorption of supplemented arachidonic acid (AA) and docosahexaenoic acid (DHA) isevaluated in a preterm. group. Design: Four newborn randomized groups were studied. Group T comprised I Iterms on regular formula. Preterms: group P (n = 9) was on a classic preterm formula. Intervention: groups PA (n = 9) and PB (n = 13) were on the same formula but PB contained AA and DHA in similar proportion to breast milk. At 20 days a 3 day metabolic balance was taken for Ca, Pi, Mg, total fat and individual fatty acids (C8 - C24, saturated unsaturated). Results: Calcium absorption was (mean +/- s.d.) 51 +/- 13% in terms. In preterms it was respectively 45 +/- 18, 38 +/- 11 and 37 +/- 21%. Total fat absorption was 92.0 +/- 8.0% in terms, and from 95.0 +/- 2.0 to 91.0 +/- 8.0% in preterms. Absorption of 8:0, 10:0 and 12:0 showed a very high and constant rate despite significant intake differences (715-33 mg/kg/day). Linoleic acid and a-linolenic acid were absorbed in the three groups at around 94% regardless of a greater LA intake in group P. Details of absorption (mg/kg/day) were: for AA, intake 17 +/- 7, fecal excretion 5 +/- 4, net retention 12 +/- 5 (75.0 +/- 18%); for DHA, intake 10 +/- 3, fecal excretion 3 +/- 2, net retention 6 +/- 4 (62.3 +/- 30%). Conclusion: Intestinal absorption of fatty acids is high and is comparablein terms and preterms as regards the studied acids. Longer acids were lesswell absorbed. The supplemented amounts of AA and DHA were less well absorbed and probably not impairing calcium absorption. Sponsorship: University of Alicante, University of Miguel Hernandez. Descriptors: fatty acid absorption; full-term and preterm; DA net retention; AA net retention.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/08/20 alle ore 13:07:24