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Titolo:
Indications and long-term outcome of treatment for benign hepatic tumors -A critical appraisal
Autore:
Terkivatan, T; de Wilt, JHW; de Man, RA; van Rijn, RR; Zondervan, PE; Tilanus, HW; IJzermans, JNM;
Indirizzi:
Univ Hosp Rotterdam Dijkzigt, Dept Surg, NL-3015 GD Rotterdam, NetherlandsUniv Hosp Rotterdam Dijkzigt Rotterdam Netherlands NL-3015 GD etherlands Univ Hosp Rotterdam Dijkzigt, Dept Hepatogastroenterol, NL-3015 GD Rotterdam, Netherlands Univ Hosp Rotterdam Dijkzigt Rotterdam Netherlands NL-3015 GD etherlands Univ Hosp Rotterdam Dijkzigt, Dept Radiol, NL-3015 GD Rotterdam, Netherlands Univ Hosp Rotterdam Dijkzigt Rotterdam Netherlands NL-3015 GD etherlands Univ Hosp Rotterdam Dijkzigt, Dept Pathol, NL-3015 GD Rotterdam, Netherlands Univ Hosp Rotterdam Dijkzigt Rotterdam Netherlands NL-3015 GD etherlands
Titolo Testata:
ARCHIVES OF SURGERY
fascicolo: 9, volume: 136, anno: 2001,
pagine: 1033 - 1038
SICI:
0004-0010(200109)136:9<1033:IALOOT>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOCAL NODULAR HYPERPLASIA; LIVER-CELL ADENOMAS; CAVERNOUS HEMANGIOMAS; GIANT HEMANGIOMAS; HEPATOCELLULAR ADENOMA; SURGICAL-TREATMENT; ECHO-PLANAR; MANAGEMENT; RESECTION; DIAGNOSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: IJzermans, JNM Univ Hosp Rotterdam Dijkzigt, Dept Surg, Dr Molewaterpl 40,NL-3015 GD Rotterdam, Netherlands Univ Hosp Rotterdam Dijkzigt Dr Molewaterpl 40 Rotterdam Netherlands NL-3015 GD
Citazione:
T. Terkivatan et al., "Indications and long-term outcome of treatment for benign hepatic tumors -A critical appraisal", ARCH SURG, 136(9), 2001, pp. 1033-1038

Abstract

Hypothesis: The natural history and clinical behavior of benign hepatic tumors during long-term follow-up may not justify primary surgical treatment. Design: Retrospective study. Setting: Tertiary referral center. Patients: Two hundred eight patients diagnosed as having a benign liver tumor between January 1, 1979, and December 31, 1999. Intervention: Seventy-four patients underwent hepatic surgery and 134 weremanaged conservatively by radiological follow-up. Main Outcome Measures: Symptoms and complications were assessed during management and follow-up. Results: In the surgically treated population, the liver lesion was symptomatic in 47 patients (64%) and an incidental finding in 27 (36%). The operative morbidity and mortality were 27% (20 of 74 patients) and 3% (2 of 74 patients), respectively. Overall, 28 (80%) of 35 patients with complaints were asymptomatic after surgery. During observation of the tumor in the conservatively managed group, 39 (87%) of 45 patients who presented with complaints were asymptomatic during a mean follow-up of 45 months; 6 patients had mild abdominal pain considered to be unrelated to the tumor. Conclusions: Conservative management of solid benign liver lesions such asfocal nodular hyperplasia and hemangioma can be performed safely, irrespective of their size. We only advise surgery for liver lesions when there is an inability to exclude malignancy or in the case of severe complaints related to the tumor. Resection is always advocated in the case of a large hepatocellular adenoma (>5 cm) to reduce the risk of rupture and malignant degeneration.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 11:12:42