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Titolo:
Biocatalysis in polymer-supported synthesis: Enzyme-labile linker groups
Autore:
Reents, R; Jeyaraj, DA; Waldmann, H;
Indirizzi:
Max Planck Inst Mol Physiol, Abt Chem Biol, D-44227 Dortmund, Germany Max Planck Inst Mol Physiol Dortmund Germany D-44227 7 Dortmund, Germany Univ Dortmund, Fachbereich 3, D-44221 Dortmund, Germany Univ Dortmund Dortmund Germany D-44221 eich 3, D-44221 Dortmund, Germany
Titolo Testata:
ADVANCED SYNTHESIS & CATALYSIS
fascicolo: 6-7, volume: 343, anno: 2001,
pagine: 501 - 513
SICI:
1615-4150(200108)343:6-7<501:BIPSEL>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIQUID-PHASE SYNTHESIS; SOLID SUPPORTS; CHEMOENZYMATIC SYNTHESIS; PROTECTING GROUP; COMBINATORIAL SYNTHESIS; PHENYLACETYL GROUP; ORGANIC-CHEMISTRY; PEPTIDE-SYNTHESIS; SOLUBLE POLYMER; OLIGONUCLEOTIDES;
Keywords:
cleavage reactions; combinatorial chemistry; enzyme catalysis; linker groups;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Waldmann, H Max Planck Inst Mol Physiol, Abt Chem Biol, Otto Hahn Str 11, D-44227 Dortmund, Germany Max Planck Inst Mol Physiol Otto Hahn Str 11 Dortmund Germany D-44227
Citazione:
R. Reents et al., "Biocatalysis in polymer-supported synthesis: Enzyme-labile linker groups", ADV SYNTH C, 343(6-7), 2001, pp. 501-513

Abstract

The development or new and broadly applicable linker groups which are stable under a variety of reaction conditions and allow release of the desired products from polymeric supports under very mild conditions is of great interest for organic synthesis and combinatorial chemistry. In this review we summarize the results of the research activities directed towards the introduction of enzyme-labile linkers which yield a variety of different target molecules through enzymatic cleavage from different polymeric supports.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 20:01:01