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Titolo:
Bone mineral density of the spine, hip and distal forearm in representative samples of the Japanese female population: Japanese population-based osteoporosis (JPOS) study
Autore:
Iki, M; Kagamimori, S; Kagawa, Y; Matsuzaki, T; Yoneshima, H; Marumo, F;
Indirizzi:
Kinki Univ, Sch Med, Dept Publ Hlth, Osaka 5898511, Japan Kinki Univ Osaka Japan 5898511 Med, Dept Publ Hlth, Osaka 5898511, Japan Tokyo Med & Dent Univ, Grad Sch, Dept Homeostasis Med & Nephrol, Tokyo, Japan Tokyo Med & Dent Univ Tokyo Japan meostasis Med & Nephrol, Tokyo, Japan Kasukabe Shuuwa Hosp, Kasukabe, Japan Kasukabe Shuuwa Hosp Kasukabe Japan sukabe Shuuwa Hosp, Kasukabe, Japan Inst Comprehens Community Care, Tokyo, Japan Inst Comprehens Community Care Tokyo Japan Community Care, Tokyo, Japan Kagawa Nutr Univ, Tokyo, Japan Kagawa Nutr Univ Tokyo JapanKagawa Nutr Univ, Tokyo, Japan Toyama Med & Pharmaceut Univ, Dept Welf Promot & Epidemiol, Toyama, Japan Toyama Med & Pharmaceut Univ Toyama Japan ot & Epidemiol, Toyama, Japan
Titolo Testata:
OSTEOPOROSIS INTERNATIONAL
fascicolo: 7, volume: 12, anno: 2001,
pagine: 529 - 537
SICI:
0937-941X(2001)12:7<529:BMDOTS>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
X-RAY ABSORPTIOMETRY; DIFFERENT SKELETAL SITES; MASS ACCUMULATION; NORMAL WOMEN; FRACTURES; STANDARDIZATION; PREMENOPAUSAL; EPIDEMIOLOGY; PREDICTION; DEFINITION;
Keywords:
bone mineral density; diagnostic criteria for osteoporosis; DXA; Japanese women; population-based epidemiologic study; prevalence rate of osteoporosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Iki, M Kinki Univ, Sch Med, Dept Publ Hlth, 377-2 Oono Higashi, Osaka 5898511, Japan Kinki Univ 377-2 Oono Higashi Osaka Japan 5898511 a 5898511, Japan
Citazione:
M. Iki et al., "Bone mineral density of the spine, hip and distal forearm in representative samples of the Japanese female population: Japanese population-based osteoporosis (JPOS) study", OSTEOPOR IN, 12(7), 2001, pp. 529-537

Abstract

Low bone mineral density (BMD) is one of the most important elements for the diagnosis of osteoporosis and screening people with higher risk of fractures. To establish the criterion value of BMD for the diagnosis of osteoporosis and to estimate the prevalence rate of osteoporosis in Japanese women,we performed a Japanese population-based osteoporosis (JPOS) study. The subjects were 4550 women aged 15 through 79 years randomly selected from seven municipalities throughout Japan. The sample size was determined to ensurethat the observed mean BMD would remain within 2.5% from the real value with a probability of 0.95 in each of the 5-year age groups. The study comprised bone mass measurements by dual-energy Xray absorptiometry at the spine (L2-4), hip and distal forearm, body size measurements and detailed interviews on medical and gynecologic history. After excluding those subjects withapparent or suggested abnormalities affecting bone mass from 3985 women (87.6%) who completed the study, 3465 women remained and served as the subjects. We present 5-year age-specific mean values of BMD and cut-off values for the diagnosis of osteoporosis according to World Health Organization (WHO) and the Japanese Society of Bone and Mineral Research (JSBMR) criteria. The cut-off levels at the spine and the distal radius proposed in this studywere similar to those proposed by the JSBMR but the cut-off level at the femoral neck in this study was 4.7% higher than that of the JSBMR. The prevalence rates of osteoporosis according to WHO criteria in the present subjects aged 50 through 79 years were calculated as 38.0% at the spine, 11.6% atthe femoral neck and 56.8% at the distal one-third site of the radius, andthose in the Japanese female population of the same age were estimated to be 35.1%, 9.4% and 51.2%, respectively. A fivefold difference was observed among the prevalence rates at different skeletal sites, which suggests thatthe different definitions of osteoporosis should be established for the different skeletal sites. The prevalence rate diagnosed at the femoral neck seemed to be lower in the present study than those reported for Caucasians. This might account for a lower incidence rate of hip fracture in Japanese women.

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Documento generato il 05/04/20 alle ore 12:43:08