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Titolo:
Management and prognosis of Merkel cell carcinoma of the eyelid
Autore:
Peters, GB; Meyer, DR; Shields, JA; Custer, PL; Rubin, PA; Wojno, TH; Bersani, TA; Tanenbaum, M;
Indirizzi:
Albany Med Ctr, Lions Eye Inst, Albany, NY 12208 USA Albany Med Ctr Albany NY USA 12208 , Lions Eye Inst, Albany, NY 12208 USA Thomas Jefferson Univ, Jefferson Med Coll, Wills Eye Hosp, Philadelphia, PA 19107 USA Thomas Jefferson Univ Philadelphia PA USA 19107 hiladelphia, PA 19107 USA Washington Univ, St Louis, MO 63130 USA Washington Univ St Louis MO USA 63130 ington Univ, St Louis, MO 63130 USA Massachusetts Eye & Ear Infirm, Boston, MA 02114 USA Massachusetts Eye & Ear Infirm Boston MA USA 02114 , Boston, MA 02114 USA Emory Univ Hosp, Atlanta, GA 30322 USA Emory Univ Hosp Atlanta GA USA 30322 ory Univ Hosp, Atlanta, GA 30322 USA Syracuse Univ, New York, NY USA Syracuse Univ New York NY USASyracuse Univ, New York, NY USA Bascom Palmer Eye Inst, Miami, FL 33136 USA Bascom Palmer Eye Inst Miami FL USA 33136 r Eye Inst, Miami, FL 33136 USA
Titolo Testata:
OPHTHALMOLOGY
fascicolo: 9, volume: 108, anno: 2001,
pagine: 1575 - 1579
SICI:
0161-6420(200109)108:9<1575:MAPOMC>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
SURGICAL-MANAGEMENT; RADIATION-THERAPY; NATURAL-HISTORY; CHEMOTHERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Meyer, DR Albany Med Ctr, Lions Eye Inst, 35 Hackett Blvd, Albany, NY 12208 USA Albany Med Ctr 35 Hackett Blvd Albany NY USA 12208 NY 12208 USA
Citazione:
G.B. Peters et al., "Management and prognosis of Merkel cell carcinoma of the eyelid", OPHTHALMOL, 108(9), 2001, pp. 1575-1579

Abstract

Objective. To evaluate the clinical presentation, treatment, and long-termfollow-up of eyelid Merkel cell carcinoma. Design: Retrospective noncomparative interventional case series. Participants: Fourteen patients with primary eyelid Merkel cell carcinoma. Methods: Cases of Merkel cell carcinoma for which long-term follow-up was available were solicited from members of the American Society of OphthalmicPlastic and Reconstructive Surgery through an on-line e-mail/news group. Main Outcome Measures: Follow-up period, treatment history, presence and type of recurrence, and mortality. Results. Average follow-up was 33.4 months. Of the 14 cases identified, only 2 patients (14%) received prophylactic therapy beyond wide surgical excision. Three patients (21%) had recurrences, none of whom initially receivedprophylactic therapy (i.e., radiation therapy, lymph node dissection, and/or chemotherapy) beyond wide surgical excision. One patient (7%) died of metastatic Merkel cell carcinoma. Conclusions: Merkel cell carcinoma is a rare skin malignancy that occasionally affects the eyelid, with the potential for regional and distant metastasis. Consideration should be given to the use of prophylactic adjunctive therapies beyond wide surgical excision while simultaneously considering themorbidity of these therapies. (C) 2001 by the American Academy of Ophthalmology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 02:24:01