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Titolo:
Metabolic and nutritional disorders in cardiac cachexia
Autore:
Mustafa, I; Leverve, X;
Indirizzi:
Harapan Pita Natl Cardiac Ctr, Intens Care Unit, Jakarta 11420, Indonesia Harapan Pita Natl Cardiac Ctr Jakarta Indonesia 11420 a 11420, Indonesia Univ Grenoble 1, Lab Bioenerget Fondamentale & Appl, Grenoble, France UnivGrenoble 1 Grenoble France t Fondamentale & Appl, Grenoble, France
Titolo Testata:
NUTRITION
fascicolo: 9, volume: 17, anno: 2001,
pagine: 756 - 760
SICI:
0899-9007(200109)17:9<756:MANDIC>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
OBSTRUCTIVE PULMONARY-DISEASE; TUMOR-NECROSIS-FACTOR; CONGESTIVE-HEART-FAILURE; ACUTE MYOCARDIAL-INFARCTION; RESTING ENERGY-EXPENDITURE; INFLAMMATORY BOWEL-DISEASE; N-3 FATTY-ACIDS; HEMODIALYSIS-PATIENTS; BODY-COMPOSITION; ELDERLY PATIENTS;
Keywords:
cardiac cachexia; anorexia; malabsorption; chronic hypoxia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
78
Recensione:
Indirizzi per estratti:
Indirizzo: Mustafa, I Harapan Pita Natl Cardiac Ctr, Intens Care Unit, S Parman St,Kav 84, Jakarta 11420, Indonesia Harapan Pita Natl Cardiac Ctr S Parman St,Kav 84 Jakarta Indonesia 11420
Citazione:
I. Mustafa e X. Leverve, "Metabolic and nutritional disorders in cardiac cachexia", NUTRITION, 17(9), 2001, pp. 756-760

Abstract

Cardiac cachexia is divided into two types, i.e., the classic type, which occurs in patients with severe heart failure, and the nosocomial type, which develops in the postoperative state. Cardiac. cachexia is due both to a decrease in nutrient intake (anorexia, malabsorption) and to specific metabolic alterations (hypercatabolism with increased energy expenditure, response to hypoxia, inflammatory status, etc). Among the various mechanisms involved in the pathogenesis of cachexia, cellular hypoxia has long been recognized. The chronic activation of the endogenous neurohormonal system is another specific feature of such patients; a striking relationship was found between cardiac cachexia and hormonal levels which correlate better than the classical parameters of cardiac failure severity. Finally, inflammatory syndrome has been known to occur frequently in patients with cardiac cachexia. Several studies have shown that tumor necrosis factor-a was significantly increased in cachectic patients and that chronic activation of the systemic immune response might be a common and unifying factor. Nutrition 2001;17:756-760. (C) Elsevier Science Inc. 2001.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 22:08:57