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Titolo:
4 ''-H-TSAO-T, a novel prototype in the HIV-1 specific TSAO family
Autore:
Lobaton, E; Velazquez, S; San-Felix, A; De Clercq, E; Balzarini, J; Camarasa, MJ;
Indirizzi:
CSIC, Inst Quim Med, E-28006 Madrid, Spain CSIC Madrid Spain E-28006CSIC, Inst Quim Med, E-28006 Madrid, Spain Katholieke Univ Leuven, Rega Inst Med Res, Louvain, Belgium Katholieke Univ Leuven Louvain Belgium a Inst Med Res, Louvain, Belgium
Titolo Testata:
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
fascicolo: 4-7, volume: 20, anno: 2001,
pagine: 711 - 714
SICI:
1525-7770(2001)20:4-7<711:4'ANPI>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMMUNODEFICIENCY-VIRUS TYPE-1; REVERSE-TRANSCRIPTASE INHIBITORS; MODIFIED NUCLEOSIDES; P51 SUBUNIT; DERIVATIVES; PYRIMIDINE; INFECTION; ANALOGS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Lobaton, E CSIC, Inst Quim Med, Juan Cierva 3, E-28006 Madrid, Spain CSIC Juan Cierva 3 Madrid Spain E-28006 E-28006 Madrid, Spain
Citazione:
E. Lobaton et al., "4 ''-H-TSAO-T, a novel prototype in the HIV-1 specific TSAO family", NUCLEOS NUC, 20(4-7), 2001, pp. 711-714

Abstract

The first TSAO derivative that lacks the amino group at the 3'-spiro moiety has been prepared. This molecule retained its HIV-1 specificity (NNRTI characteristic) but did not select for any of the classical NNRTI-specific mutations in the NNRTI binding pocket, including 138-Lys (TSAO resistant strain).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:54:59